www.onkologiecs.cz 189 / Onkologie. 2024;18(3):184-189 / ONKOLOGIE HLAVNÍ TÉMA Adjuvantní léčba renálního karcinomu – nové výsledky studie KEYNOTE-564 LITERATURA 1. Dusek L, Muzik J, Kubasek M, et al. Epidemiology of Malignant Tumours in the Czech Republic [Internet]. Brno: Masaryk University; 2005 [cited 2023 May 3]. Available from: www.svod.cz. 2. Hsieh JJ, Purdue MP, Signoretti S, et al. Renal cell carcinoma. Nat Rev Dis Prim. 2017;3:17009. 3. Chowdhury N, Drake CG. Kidney Cancer: An Overview of Current Therapeutic Approaches. Urol Clin North Am. 2020;47(4):419-431. 4. Larcher A, Fallara G, Rosiello G, et al. Cytoreductive Nephrectomy in Metastatic Patients with Signs or Symptoms: Implications for Renal Cell Carcinoma Guidelines. Eur Urol. 2020;78(3):321-326. 5. Poprach A, Holanek M, Chloupkova R, et al. Cytoreductive nephrectomy and overall survival of patients with metastatic renal cell carcinoma treated with targeted therapy – data from the national renis registry. Cancers (Basel). 2020;12(10). 6. Escudier BJ, Rini BI, Martini J-F, et al. Phase III trial of adjuvant sunitinib in patients with high-risk renal cell carcinoma (RCC): Validation of the 16-gene Recurrence Score in stage III patients. J Clin Oncol [Internet]. 2017;35(15_suppl):4508. Available from: http://ascopubs.org/doi/abs/10.1200/JCO.2017.35.15_ suppl.4508. 7. Haas NB, Manola J, Dutcher JP, et al. Adjuvant Treatment for High-Risk Clear Cell Renal Cancer: Updated Results of a High-Risk Subset of the ASSURE Randomized Trial. JAMA Oncol. 2017;3(9):1249-1252. 8. Motzer RJ, Haas NB, Donskov F, et al. Randomized Phase III Trial of Adjuvant Pazopanib Versus Placebo After Nephrectomy in Patients With Localized or Locally Advanced Renal Cell Carcinoma. J Clin Oncol. 2017;35(35):3916-3923. 9. Ryan CW, Tangen CM, Heath EI, et al. Adjuvant everolimus after surgery for renal cell carcinoma (EVEREST): a double- -blind, placebo-controlled, randomised, phase 3 trial. Lancet (London, England). 2023;402(10407):1043-1051. 10. Pal SK, Uzzo R, Karam JA, et al. Adjuvant atezolizumab versus placebo for patients with renal cell carcinoma at increased risk of recurrence following resection (IMmotion010): a multicentre, randomised, double-blind, phase 3 trial. Lancet (London, England). 2022;400(10358):1103-1116. 11. Allaf ME, Kim SE, Master VA, et al. PROSPER: Phase III RandOmized Study Comparing PERioperative nivolumab versus observation in patients with renal cell carcinoma (RCC) undergoing nephrectomy (ECOG-ACRIN EA8143). J Clin Oncol [Internet]. 2021;39(15_suppl):TPS4596–TPS4596. Available from: https://doi.org/10.1200/JCO.2021.39.15_suppl.TPS4596. 12. Motzer RJ, Russo P, Grünwald V, et al. Adjuvant nivolumab plus ipilimumab versus placebo for localised renal cell carcinoma after nephrectomy (CheckMate 914): a double- -blind, randomised, phase 3 trial. Lancet (London, England). 2023;401(10379):821-832. 13. Choueiri TK, Tomczak P, Park SH, et al. Adjuvant Pembrolizumab after Nephrectomy in Renal-Cell Carcinoma. N Engl J Med. 2021;385(8):683-694. 14. Choueiri TK, Tomczak P, Park SH, et al. Overall Survival with Adjuvant Pembrolizumab in Renal-Cell Carcinoma. N Engl J Med. 2024;390(15):1359-1371. Pro vás a vaše pacienty vysíláme PODCASTY V podcastových aplikacích hledejte HOVORY O MEDICÍNĚ NOVĚ: Kdy nám zdravotní a sociální systém podává pomocnou ruku? Medicínské informace ze Solenu můžete získávat nejen v tištěné podobě, na kongresech nebo z on-line kurzů, ale máme i podcastový kanál. Více na www.solen.cz
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