572
ONKOLOGIE3418040010760120167227269329388409453
/8408040010731
Onkologie.9168040010761110147195214263313331375390
2024;18(5):300-3041326804001074487128168182220259283325348362407450496526567610656
/20278040010732
www.onkologiecs.cz48658040010765133201214262311348396415464514532576617652669709748
3001248020012657114173
HLAVNÍ341200012670127198263336370
TÉMA733200012657114204274
Náhodný34136001063979120161201242279
nález63636001063979110142177
adenokarcinomu82936001063777109150191227269304339357398438492533
děložního137836001063769100140171212230271311
čípku17053600106335085120162
po188236001063374
komplikaci197236001063372126161192209245287320338
císařského23253600106335083123158192227260301342
řezu268236001063466100141
Náhodný3409200298166292430567709848967
nález13569200298140265329454566
adenokarcinomu197092002981272683935336707989251014112111861324146116661803
děložního382292002981432683344715817227869301066
čípku49379200298108173314443582
po34011800298144281
komplikaci6701180029813026346861067573886799310991163
císařského1882118002981081732754014905947238459851122
řezu30521180029891217329468
František340158001375897154219259289337395456
Velčický1,8181580013770123154204235284344405122115900803651
2,128515900803613231580013729
Monika13741580013793157221251311369
Náležinská1,17661580013775134164222274305370417477536229415900803651
2,235815900803623961580013729
Jiří2447158001374575117147
Nagy3,26161580013776135199257287115900803629081580013729
Josef29591580013745109156214252
Chovanec1,32341580013765129192249307371429479371115900803651
23775159008036
1Oddělení3401740078333711740013376139200255281336397422
gynekologické8161740013361114175230282340366426488513562613666
onkologie15051740013361122173231257317379404459
Kliniky1988174001335986111171196247302
operační23131740013360123179214267316376401
onkologie27371740013361122173231257317379404459
Masarykova32201740013388141183237272327379438489542
onkologického37851740013361121172231257317379404453503557618678
ústavu,44861740013361103140193244305327
Brno4837174001335995156216
2Oddělení3401890078333731890013376139200255281336397422
gynekologické8181890013361114175230282340366426488513562613666
onkologie15071890013361122173231257317379404459
Kliniky1990189001335986111171196247302
operační23151890013360123179214267316376401
onkologie,27391890013361122173231257317379404459481
Lékařská32431890013352106158211246290341395
fakulta3661189001333286136197222258311
Masarykovy39961890013388141183237272327379438489544
univerzity,45641890013360121145198252287336361397452469
Brno5056189001336095156217
3Gynekologicko-porodnické340204007833373204001337112118323828934837443449652157062067971677984087693599810581083113211821236
oddělení,16322040013361123185240265320381406428
Nemocnice20832040013373128220280330390415464517
Milosrdných26232040013389114140200243278339399449497557
bratří,3203204001336399151187222247269
Brno3496204001335995156216
Karcinom3402550012154103136180203258313397
děložního7552550012157107131186228283306364419
čípku1192255001214568124172227
je1437255001212575
jednou1530255001212475132187242298
z18462550012143
nejčastějších19072550012155106130174223262296345369407430475530
malignit24552550012184132155178234289313346
zjištěných281925500121436790128162211267312356411
v32482550012148
průběhu3315255001215790145201252308363
těhotenství.36962550012133823402690012155109141190245283316366389409
Většina7672690012155102135174197251299
případů1083269001215688111167215271325
je1425269001212474
zjištěna151626900121426688126159208262310
v18432690012147
časném1908269001214492130184234317
stadiu2242269001213972120176199252
onemocnění.25122690012154109159241295340395444499522542
Časná30712690012157105143198245
diagnostika3333269001215679126181235290328362384430478
se340283001213990
opírá4472830012155112135168216
o6812830012154
screeningové753283001214084117166217272295350406460507556
vyšetření1327283001214898137187220253302357380
v17252830012148
I.1791283001212345
trimestru185328300121336689172222261295327382
těhotenství.2253283001213382137192225273329367401451475495
Vzhledem2766283001215698153176226283333416
k32002830012147
těhotenským3264283001213382138192225274329368414464548
změnám3402970012143126177233281364
na7322970012156104
děložním8642970012157107131186228284307391
hrdle1283297001215588144168218
jsou1529297001212564119174
nálezy17322970012155103127177221271
obtížně20312970012155112145169212267318
hodnotitelné,23772970012156111168224279312335368417441497547567
s29722970012140
tendencí3040297001213383139195246301347370
k34382970012147
falešné3513297001212978102152192247298
pozitivitě.3403110012157113155178211234282306339389408
Péče7753110012153101147196
o9973110012155
pacientku10793110012157106150173224279312358413
a15193110012148
plod1594311001215781136193
by18143110012157103
měla19443110012184134158206
být21773110012156103139
v23433110012148
rukách2418311001213288135184229284
multidisciplinárního27283110012184139162195218274298336381404461485508563611644700723780835
týmu3590311001213383167222
s3403250012140
individualizovanou401325001212378135158207230287342390413436479533581629684739795
léčbou1217325001212374119176232287
a15253250012148
s15953250012139
respektováním1655325001213383122179230277313367414463518541624
přání2301325001215689138193216
pacientky.25383250012157106151174224279312358409425
Placenta340339001215274122166214269301350
accreta708339001214791135167216249297
je1023339001212474
nejčastějším11153390012154104128172220259292341364403426508
typem1641339001213282138189271
abnormálně19303390012148104159213246328376399453503
invazivní2451339001212378123171214237285340363
placenty2833339001215579127171219274306356
(AIP).3207339001212887110163189207
Ultrazvukové34323390012164871201522002432933483403530012146100146195
vyšetření554353001214798137187220253302357381
má9533530012182130
své1102353001213988137
nezastupitelné12573530012155105148198237270325381405438487511566616
místo18923530012182105144177231
zejména2142353001214292116198248304351
v25123530012147
časné2578353001214492131186236
diagnostice2833353001215579126182237292331364388432481
abnormální33333530012147103159213246329377401455479
invaze340367001212379127176220271
trofoblastu.631367001213366122151207265290339379414469491
Mezi11423670012180132176200
hlavní1362367001215580128176233257
rizikové1639367001213257100125172226274324
faktory1983367001212979127163218252303
abnormální23063670012148106162218252336385410466490
nidace2815367001215680137186231281
patří31163670012157106140173197
císařský3333367001214569108158191232280331
řez3684367001213283127
v3403810012148
anamnéze4113810012148105154238294346390441
(nebo875381001212982133192249
jiné1147381001212448104156
předchozí1326381001215791142200246302358401425
operace17743810012155113165199249295345
na21423810012155104
děloze,22703810012156107132188231282303
kyretáž)2596381001214798133184218268312341
a29603810012149
vyšší30323810012148100140180204
věk3259381001214898146
matky.34283810012184133166214265283
Klíčová340397001246291119165223276330
slova:697397001244473131184238264
adenokarcinom9883980012149106157213269317367400445468524580665
děložního16813980012157108132188231287311368424
čípku,2134398001214569126174230251
těhotenství,2414398001213383140195229279335374409460484505
krvácivé2948398001214782134183228252301350
komplikace33273980012147102186244268292339389434484
porodu,3404120012157113146200258312333
peripartální6944120012157108141165221270302338387411466489
život1204412001214366114168201
ohrožující14264120012155111143198240295319342387410
krvácení,1857412001214781132180225274330353373
abnormálně22524120012148105160215248332380404459509
invazivní2782412001212479125174217241289345368
placenta.3171412001215781129174223279311360381
Incidental340439001242888133161221274334370424452
finding812439001243463122182210269328
of1160439001245893
cervical1273439001244598136192220265319347
adenocarcinoma16404390012453112166225283329382421466494553611698751
after2411439001245387127180219
complication26504390012445102189249277305350404440469527586
of340453001245892
caesarean453453001244598151195249287341394453
section926453001244497143182210268327
Carcinoma3404710012158105137180202256310393440
of804471001215583
the911471001213387136
uterine1071471001215587135167190244294
cervix1388471001214593125175198244
is1655471001212462
the1740471001213387137
most19014710012183137176208
frequent2133471001212962111167220270324356
malignant25134710012183130152174229284331385416
disease2953471001215679116166213251300
diagnosed3277471001215679125180235289327377433
in3734471001212377
pregnant340485001215789138193248295349380
women.7404850012174127209259314334
Most10944850012180134173205
cases1319485001214593131180219
are1557485001214880129
early1705485001215098129152198
carcinomas1923485001214592124167189243297380427465
due24084850012156110159
to2587485001213386
cervical2693485001214492124174197241289311
screening3024485001213983115164214268290345400
methods34434850012184133166220274330368
(PAPP340499001212880134186237
smear,6014990012140122171218250265
HPV8904990012166118173
DNA10874990012167132192
testation1303499001213482120153201233255309363
and16914990012148102158
colposcopy).1874499001214497120176230269313366422467493510
However24094990012165119191240286335366
sometimes2800499001214094176226258281363412451
the3275499001213388137
results3437499001213281120173195227267
of3729499001215483
the340513001213387137
examination493513001215096143225247302349380402456511
are1020513001214879128
unclear11645130012155109153176225272303
due14835130012157110160
to1659513001213386
the1761513001213387136
physiological19135130012157112156195217271294348404426469517539
pregnancy2468513001215789138194248295349393442
associated2926513001214886124178223245291323371427
changes3369513001214599146200255305343
of3728513001215583
the340527001213387137
cervical495527001214593125175198242289312
epithelium8265270012150106128160215264287309363445
(squamous1289527001212965121175222304358412450
of1758527001215583
the1860527001213387136
vaginal2015527001214896151173227274297
portion23305270012157112144179201255310
and26585270012149103159
columnar2835527001214598121174257311358389
of3243527001215583
the3345527001213387137
cervical3500527001214593125175198242289312
canal).340541001214490143189210236253
Cervical6085410012157103134183205247294315
cancer938541001214490143186232263
complicating1216541001214495176230252273316362393414467520
pregnancy1751541001215687134189242287340383430
is2196541001212359
a22705410012147
specific2332541001213993142185206234258300
clinical264754100121446586139160203249270
situation,293254100121396091143189220241293347365
that3312541001213385131161
requires3488541001213280134187208238286323
individual340555001212377131153199222276329375397
approach,7525550012148103158190242289332385404
multidisciplinary11725550012182135157188210265286323367388443465487540586617666
experienced1853555001214995150200231253301355398445501
team2369555001213380126207
of2592555001215481
specialists2689555001213993143187208254276297334367405
in3110555001212376
gynaecological32015550012156102156202251295347369422477499542589610
oncology3405690012155110154206229283339386
and7455690012148103158
in922569001212478
obstetrics,10195690012155111150183231263295317361401421
respecting1459569001213381120175226270305327381436
the1914569001213387137
opinion20705690012155111134188210264319
of2408569001215583
the2510569001213387137
pregnant2666569001215789138193248295349380
woman.30655690012174127210257311331
Placenta340583001215375123167216271303351
accreta709583001214892136168217250299
represents1025583001213382139171221260310365397437
the1480583001213388138
most16355830012183138177210
frequent1863583001212962112168223273328360
type2240583001213383140191
of2448583001215584
abnormally25495830012148104160214247330378401424471
adherent30385830012148104159209241291346378
placenta,3433583001215781128173221277309357378
where3405970012174129180213262
placental621597001215781129174223279311360383
villi102359700121487295118141
are1183597001214881130
attached1332597001214881116165210265315373
to1723597001213387
the1829597001213388139
myometrium.19865970012184130184267318351384407462545566
Placenta2571597001215376124169218273306354
accreta2944597001214893137169219252301
may32645970012183131177
be34605970012157108
ultrasonically3587597001215578111144192340611001214095150173218266290313360
diagnosed718611001215679127183238293332383440
antepartum.11766110012148103135184241290322358413496517
The17116110012150106156
main18856110012183131154209
etiological2112611001215084107162185241297320365413437
factors2567611001212978122157211244284
are2869611001214881130
previous3017611001215790140187211266321360
caesarean3395611001214493143183231264313361416
section340625001214090136171194249305
scar668625001213984133165
(or856625001212980113
other992625001215588143193226
previous1241625001215790140187211266322361
uterine1624625001215689138171194250300
incisions,1947625001212379124147185208263319358379
uterine2349625001215588137170194249299
curettage)26716250012145100132182216251300356406432
and31256250012149104161
older3308625001215579136186219
age35506250012148104155
of3728625001215484
pregnant340639001215790140196252300355387
women.7496390012173127211261317338
Key3406550012461111161
words:5186550012476132169228270294
adenocarcinoma8296560012148103152206260304351382425446500554636682
of1529656001215583
the1630656001213386135
uterine1783656001215587135166188242291
cervix,2092656001214592124173196241261
pregnancy,2371656001215789137192246293346390438453
obstetrical28416560012155111149181229261292314357404426
hemorrhage,32856560012156105187240272303358404459508526
life-threatening34067000121234470118148179231261307352382429481502554607
obstetrical9606700012154108145176222253283304346391412
hemorrhage,13866700012154102182234264294347392445492510
abnormally19096700012148101154206236316361382403447
adherent23706700012147101153200231277330360
placenta2743670001215677122164210263293339
–30956700012149
placenta3158670001215677122164210263292338
accreta.3510670001214789130159206237283301
Vlastní3407170014772104166216259328359
kazuistika7277170014761123178246277328371402463525
Pacientka,480734001094889128147191240267308350368
37866734001094687
let,97173400109216594111
tercigravida,1100734001093073101139158207235277318338387429447
sekundipara1564734001093680121169218267287336379406449
byla340748001095089108149
pravidelně500748001095077118157176224266285332374
sledována88574800109355396144191230271318358
v12547480010942
těhotenské1307748001092971118164191233280312351392
poradně1710748001095098125165213260302
u3407620010950
registrujícího402762001092973122142175204232280300320358377427475
gynekologa.890762001095092141185226273293341390432450
Onkologická13527620010962111152199219267317336375415458
cytologie1822762001094184115162340776001092169119139182
z5367760010939
čípku588776001094160109151199
děložního801776001095094114163199247267317365
a11807760010943
z12377760010938
hrdla1289776001095078127147188
byla1491776001095192112154
odebrána1659776001094999143193221263312353
měsíc21407200010975119153172211
před2365720001095280123173
začátkem2553720001093881120162190231273347
těhotenství2914720001093073122170198241290323352396416
s33457200010935
negativním3395720001095093143185213232274323343416
výsledkem2140734001094488123143187238279323397
pro2560734001095180128
onkologicky27107340010950100141188209258308328367408453
suspektní3185734001093684118168214255287336355
buňky,35627340010952101150191236249
pacientka2140748001095194133152195244272312355
neprodělala2508748001094993143172219269313333375394436
očkování2957748001094989129176217259307326
proti3296748001095179127155174
lidskému348374800109214090124164207280328
papilomaviru2140762001095194143163183231305347387407435483
(HPV),2637762001092682129177204219
neměla2870762001095094168212232273
v31577620010943
anamnéze3214762001094392134207255299337380
cervikální36087620010940831111561762140776001094286105154173
prekancerózu.2335776001095280124165208257296339368416452501518
Pacientka2875776001094890129148192241269310353
se3250776001093680
dlouhodobě3352776001095171120168217265316364414459
DECLARATIONS:4068257008648871301662142563043393604124625014570257008514
Declaration406827100874987120141179206244271291333375
of445727100874066
originality:45372710087406888130150192230251271298337356
The406828200853473109
manuscript418828200855891130168195227249266306329
is452828200851744
original45832820085386178117133172205222
and481628200853472112
has49392820085387299
not50502820085387699
been516128200853975110149
published532228200853977117134150177216251291
or406829300853862
submitted414529300852867108167184208234269310
elsewhere.44702930085355381117169209245269305320
Ethical406830700873764107127160198218
principles43003070087427090132165185228249287319
compliance:463330700873173134177197218256298330368387
The406831800853678116
authors420531800853475100142183208238
attest44643180085356087124153179
that466431800852465101126
their481131800852465103121146
study49783180085295595138173
was517331800855389118
approved531231800853577120145186221258301
by406832900854073
the41583290085236399
local42743290085175689124141
Ethical44323290085345898115147182199
Committee464832900854179139198215239265300337
and500232900853373113
is513232900851745
in519432900851656
compliance526732900853169129169187204239278311346
with40683400085537298140
human423634000854081143180221
studies44863400085285596139157195226
and474034000853577119
animal48883400085347695156193212
welfare512834000855391110133170196234
regulations53903400085236110414516420140683510085234080120148
of423535100853960
the43153510085236399
authors’44343510085347397136176200229244
institutions46983510085165684109126150189213231270310338
as505635100853462
well513835100855187104122
as527935100853462
with53613510085526993133
the55143510085236299
World406836200856099124142184
Medical427336200855795137155188224242
Association453536200854474104144178196231256273314355
Declaration491136200854785119136172196232257274315356
of528836200853961
Helsinki537036200854684102131149189224243
on406837300853878
Ethical41653730085355898115147182199
Principles43833730085376178117150167207225261290
for46923730085205983
Medical479437300855693134151183218235
Research504837300853874102139173197229268
Involving53353730085175690128146181198238278
Human406838400854685145179219
Subjects430738400853474114132168201227256
adopted458338400853474114155179215256
by485838400854074
the49523840085236399
18th507138400853669514138500501437
WMA5198384008559116160
General537838400854582122158182217235
Assembly406839500854475105143204247266302
in439339500851758
Helsinki,447439500854785104134152193228248264
Finland,47613950085355394113149190232249
in503339500851758
June511539500852667109147
1964,528539500853771110150166
with54743950085537297139
subsequent406840600852867107136172213252288328352
amendments,443740600853493130169210269305345369398414
as486840600853462
well494840600855287105122
as508840600853362
with51674060085526993133
the53184060085236298
ICMJE543440600851759116143179
Recommendations406841700853977112153216278317359402439465483525568598
for46974170085226389
the481841700852466104
Conduct,495441700854283125168210245272290
Reporting,527541700853978121163189217236278321338
Editing,40684280085347491115132172212227
and430842800853373113
Publication443442800853776117134151183218242259298338
of478542800853859
Scholarly485742800853467106146163198221239273
Work514242800856097121155
in531042800851656
Medical537842800855693134151183218235
Journals,406843900852666105129169204221249265
updated435343900853980121155179215256
in462943900851656
December470543900854683116151211252289313
2018,503743900853673107140156
including52134390085165689106145186203243283
patient55164390085407540684500085234076116140
consent422245000853270110138174214238
where447545000855191127151187
appropriate.467745000853474115139178219243260295318354369
Conflict406846400874282124149171191223251
of433446400874065
interest44134640087196288126154192224251
and467846400873779122
financial48144640087244587125167200220258279
disclosures:51074640087416293126147188220261289327359378
None.406847500854686126162177
Funding/Support:406848900873777119162183225267291329371414457499526554574
Podpořeno406850000853775116157197221256296336
MZ441950000855696
ČR452950000854179
–4623500008535
RVO467350000853777125
(MOÚ,481350000852076125171185
00209805).501350000853674109145182219256293312326
Supported406851100853574114155195219245280321
by440451100854073
MH4492511008557103
CZ461051100854181
–4706511008535
DRO475651100854685135
(MMCI,490551100852076134175192208
00209805).512851100853674109145182219256292312326
Cit.4068714008541588297
zkr:41807140085306489105
Onkologie.429971400864991127167186227268287324342
2024;18(5):300-304465571400863876113150167203239261297318335373411451476513551590
https://doi.org/10.36290/xon.2024.062406872500853962881291571721982194284725008641811004385725008514547811714345287250086387390130169206244283307342382423441481519556594611650689727
Článek40687360085415892132168202
přijat4285736008539638198132156
redakcí:445673600852359100134168199216231
28.47017360085367288
8.480473600853652
2024487173600853672107142
Článek40687470085415892132168202
přijat4285747008539638198132156
k4456747008533
tisku:45047470085234068101141156
8.467574700853652
9.474174700853650
2024480674700853572107141
MUDr.4068766008759108158186202
František428476600873763101143169190222260299
Velčický459776600874580101134155187226266
frantisek.velcicky@mou.cz40687780085204580119143160188224258275307342360392409441475511562621661701716748780