ONKOLOGIE / Onkologie. 2025;19(4):214-218 / www.onkologiecs.cz 218 PŘEHLEDOVÉ ČLÁNKY Durvalumab v léčbě limitovaného stadia SCLC a nemůžeme očekávat zázrak v podobě vynalezení léku s excesivním účinkem na sílu a trvání léčebné odpovědi. Zlepšení parametrů OS a PFS, kterých bylo dosaženo ve studii ADRIATIC, představuje výrazný příznivý „skok“ v léčbě, proto lze souhlasit s názorem autorů, kteří označují přidání durvalumabu po absolvování chemoradioterapie za revoluční léčbu LD-SCLC. LITERATURA 1. Rudin CM, Brambilla E, Faivre-Finn C, Sage J. Small-cell lung cancer. Nat Rev Dis Primers. 2021;7(1):3. doi: 10.1038/ s41572-020-00235-0. 2. Kim SY, Park HS, Chiang AC. Small Cell Lung Cancer: A Review. JAMA. 2025;333(21):1906-1917. doi:10.1001/ jama.2025.0560. 3. Jett JR, Schild SE, Kesler KA, et al. Treatment of small cell lung cancer: Diagnosis and management of lung cancer, 3rd ed: American College of Chest Physicians evidence-based clinicla practice guidelines. 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