Onkologie. 2012:6(6):298-303

Invasive fungal diseases in hematological patients - epidemiology, risk factors, clinical sings and diagnostics

Martina Tošková1, Jana Winterová1, Iva Kocmanová2, Zdeněk Ráčil1,3
1 Interní hematologická a onkologická klinika, Masarykova univerzita a Fakultní nemocnice Brno
2 Oddělení klinické mikrobiologie, Fakultní nemocnice Brno
3 CEITEC &ndash, Central European Institute of Technology, Masarykova univerzita, Brno

Invasive fungal infections are serious life-threatening complication in immunocompromised patients. They are rare in comparison with

bacterial infection but attributable mortality is higher. Last two decades brought significant changes in epidemiology of invasive fungal

diseases and the last few years brought much progress in diagnostics and treatment.

Keywords: invasive fungal infections, risk factors, clinical sings, diagnostics

Published: December 1, 2012  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Tošková M, Winterová J, Kocmanová I, Ráčil Z. Invasive fungal diseases in hematological patients - epidemiology, risk factors, clinical sings and diagnostics. Onkologie. 2012;6(6):298-303.
Share...
Download citation
  • BibTeX (.bib)
  • Bookends (.ris)
  • EasyBib (.ris)
  • EndNote (.enw)
  • EndNote 8 (.xml)
  • ISI WoS (.isi)
  • Medlars (.medlars)
  • Mendeley (.ris)
  • MODS (.xml)
  • Papers (.ris)
  • RefWorks (.txt)
  • RefManager (.ris)
  • RIS (.ris)
  • MS Word (.xml)
  • Zotero (.ris)
    • Open full article

    References

    1. Pfaller MA. Invasive Fungal Pathogens: Current Epidemiological Trends. Clin Infect Dis 2006; 43(Suppl 1): 3-14. Go to original source...
    2. Pagano L, et al. Invasive aspergillosis in patients with acute myeloid leukemia: a SEIFEM-2008 registry study. Haematologica 2010; 95: 644-650. Go to original source... Go to PubMed...
    3. Hachem R, et al. Clinical and radiologic predictors of invasive pulmonary aspergillosis in cancer patients. Cancer 2006; 106: 1581-1586. Go to original source... Go to PubMed...
    4. Neofytos D, et al. Epidemiology and outcome of invasive fungal infection in adult hematopoietic stem cell transplant recipients: analysis of Multicenter Prospective Antifungal Therapy (PATH) Alliance registry. Clin Infect Dis 2009; 48(3): 265-273. Go to original source... Go to PubMed...
    5. Kontoyiannis DP, et al. Prospective surveillance for invasive fungal infections in hematopoietic stem cell transplant recipients 2001-2006: overview of the Transplant-Associated Infection Surveillance Network (TRANSNET) Database. Clin Infect Dis 2010; 50: 1091-100. Go to original source... Go to PubMed...
    6. Roden MM, et al. Epidemiology and outcome of zygomycosis: a review of 929 reported cases. Clin Infect Dis 2005; 41: 634-653. Go to original source... Go to PubMed...
    7. von Eiff M, et al. Pulmonary aspergillosis: early diagnosis improves survival. Respiration 1995; 62: 341-347. Go to original source... Go to PubMed...
    8. Racil Z, et al. Intravenous PLASMA-LYTE as a major cause of false-positive results of platelia Aspergillus test for galactomannan detection in serum. J Clin Microbiol 2007; 45: 3141-3142. Go to original source... Go to PubMed...
    9. Walsh TJ, et al. Detection of galactomannan antigenemia in patients receiving piperacillin-tazobactam and correlations between in vitro, in vivo, and clinical properties of the drug-antigen interaction. J Clin Microbiol 2004; 42: 4744-4748. Go to original source... Go to PubMed...
    10. Pfeiffer CD, Fine JP, Safdar N. Diagnosis of invasive aspergillosis using a galactomannan assay: a meta-analysis. Clin Infect Dis 2006; 42: 1417-1427. Go to original source... Go to PubMed...
    11. Racil Z, et al. Galactomannan detection in bronchoalveolar lavage fluid for the diagnosis of invasive aspergillosis in patients with hematological diseases-the role of factors affecting assay performance. Int J Infect Dis 2011; 15: 874-881. Go to original source... Go to PubMed...
    12. Karageorgopoulos DE, et al. beta-D-glucan assay for the diagnosis of invasive fungal infections: a meta-analysis. Clin Infect Dis 2011; 52: 750-770. Go to original source... Go to PubMed...
    13. De Pauw B, et al. Revised definitions of invasive fungal disease from the European Organization for Research and Treatment of Cancer/Invasive Fungal Infections Cooperative Group and the National Institute of Allergy and Infectious Diseases Mycoses Study Group (EORTC/MSG) Consensus Group. Clin Infect Dis 2008; 46: 1813-1821. Go to original source... Go to PubMed...

    Return to the content


    Oncology

    Madam, Sir,
    please be aware that the website on which you intend to enter, not the general public because it contains technical information about medicines, including advertisements relating to medicinal products. This information and communication professionals are solely under §2 of the Act n.40/1995 Coll. Is active persons authorized to prescribe or supply (hereinafter expert).
    Take note that if you are not an expert, you run the risk of danger to their health or the health of other persons, if you the obtained information improperly understood or interpreted, and especially advertising which may be part of this site, or whether you used it for self-diagnosis or medical treatment, whether in relation to each other in person or in relation to others.

    I declare:

    1. that I have met the above instruction
    2. I'm an expert within the meaning of the Act n.40/1995 Coll. the regulation of advertising, as amended, and I am aware of the risks that would be a person other than the expert input to these sites exhibited

    No
    Yes

    If your statement is not true, please be aware
    that brings the risk of danger to their health or the health of others.