Onkologie. 2008:2(2):123-127

Výskyt nádorových onemocnění u pacientů po transplantaci srdce

Lenka, Hošková1, Ivan. Málek1, Mariana Podzimková, Mariana. Podzimková1, Jan Pirk1, Pavel. Trunečka2, Martin, Kment3
1 Klinika kardiologie, Institut klinické a experimentální medicíny, Praha
2 Transplantcentrum, Institut klinické a experimentální medicíny, Praha
3 Patologicko-anatomické pracoviště, Institut klinické a experimentální medicíny, Praha

Úvod: Nádorová onemocnění se u pacientů po transplantaci srdce vyskytují 4–7× častěji než v běžné populaci a rychleji progredují. Cílem práce bylo zjistit výskyt nádorů v různě dlouhém období od transplantace a rozložení jednotlivých typů nádorů.

Metodika: Od ledna 1984 do prosince 2007 bylo v IKEM provedeno 670 transplantací srdce, z toho u 556 mužů a 114 žen. Základním onemocněním byla u 49 % kardiomyopatie, u 40 % ischemická choroba srdeční. Po transplantaci byli pacienti sledováni v pravidelných 3–4měsíčních intervalech, v prvním roce častěji. Diagnóza byla stanovena na základě klinických příznaků, odchylek v laboratorních nálezech a za pomoci zobrazovacích metod. Všem pacientům s nádorem byla upravena imunosupresivní léčba.

Published: August 1, 2008  Show citation

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Hošková L, Málek I, Podzimková M, Podzimková M, Pirk J, Trunečka P, Kment M. Výskyt nádorových onemocnění u pacientů po transplantaci srdce. Onkologie. 2008;2(2):123-127.
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