Onkologie. 2009:3(3):141-146

Epidemiology of non-Hodgkin’s lymphoma in Czech Republic, Europe and the United States

MUDr. Tomáš Papajík CSc¹, Marek Trněný², Ingrid Vášová³, David Belada⁴, Milada Jankovská⁵, MUDr. Pavel Jindra⁶, Jan Mužík⁷, Tomáš Pavlík⁷, Ladislav Dušek⁸, Karel Indrák¹

¹ Hemato-onkologická klinika FN a LF UP v Olomouci

² I. interní klinika 1. LF UK a VFN Praha

³ Interní hematoonkologická klinika LF MU a FN Brno

⁴ 2. interní klinika - oddělení klinické hematologie FN Hradec Králové

⁵ Oddělení klinické hematologie FNKV Praha

⁶ Hematologicko-onkologické oddělení, FN Plzeň

⁷ Institut biostatistiky a analýz, Masarykova univerzita, Brno

⁸ ředitel Institutu biostatistiky a analýz Masarykovy univerzity v Brně

Non-Hodgkin´s lymphoma (NHL) represents the fifth most common cancer in Western countries. It comprises a heterogeneous group

of malignant tumors of the lymphoid tissue with distinctive cell lineage, histopathology, genetic profile, clinical features, and possibly

distinct causes. The overall incidence of NHL increased steeply in most developed areas of the world between the 1970s and the mid-

1990s. The increase has been seen for males and females, for all races and age groups of adult peoples. Recent reports suggest that the

incidence have slowed in the late 1990s, nevertheless are still increasing by approximately 1–2 % annually. The reasons for these increases

are poorly understood. Population-based 5-year relative survival improved considerably in the beginning of 21st century and exceeded

60 % both in the USA and the Czech Republic. Also the decline in death rates for NHL has been evident in all Western countries during

last decade. For further better analysis of incidence and survival of distinct NHL subtypes we should pay great attention to standardize

diagnostic and reporting accuracy and maybe to modification and harmonization of cancer registries structure.

Keywords: lymphoma, incidence, mortality, survival.

Published: June 15, 2009  Show citation