Onkologie. 2009:3(4):251-253

Toxoplazma infection of the central nervous system in a female patient in long-term remission of Hodgkin lymphoma

Peter Turcsányi2, Vít Procházka2, Renata Urbanová1, MUDr. Tomáš Papajík CSc2, Luděk Raida2
1 II. interní klinika 3. lékařská fakulta Univerzity Karlovy a Fakultní nemocnice Královské Vinohrady, Praha
2 Hemato-onkologická klinika FN a LF UP v Olomouci

We present a case of 45 years old woman with Hodgkin´s lymphoma, 5 years in complete remission, after primary chemo and radiotherapy.

It seems that the immune system has not recuperated yet, and in the patient was diagnosted active toxoplasmosis with not quite

typical symptoms. It was successfully treated with intensive antitoxoplasmosis therapy.

Keywords: toxoplasmosis, Hodgkin´s lymphoma, immune system, polymerase chain reaction, serology.

Published: November 1, 2009  Show citation

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Turcsányi P, Procházka V, Urbanová R, Papajík T, Raida L. Toxoplazma infection of the central nervous system in a female patient in long-term remission of Hodgkin lymphoma. Onkologie. 2009;3(4):251-253.
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    References

    1. Del Valle L, Pina-Oviedo S. HIV disorders of the brain; pathology and pathogenesis. Front Biosci. 2006; 11: 718-732. Go to original source... Go to PubMed...
    2. Zelman I, Mossajkovski M. Opportunistic infections of the central nervous system in the course of acquired immune deficiency syndrome (AIDS). Morphological analyssis of 172 cases. Folia Neuropathol. 1998; 36: 129-144. Go to PubMed...
    3. Brew B. Toxoplasmosis. In: Brew B, ed. HIV Neurology. Oxford: Oxford University Press, INC, 2001.
    4. Subauste C, Wong S, Remington J. AIDS-associated toxoplasmosis. In: Sande M, Volberding P, eds. The Medical Management of AIDS. Philadelphia: W. B. Saunders Company, 1997.
    5. Machala L, Kodym P, Rozsypal H, Staňková M, Sedláček D. Doporučený postup diagnostiky a terapie toxoplazmózy u osob s HIV infekcí. Klin mikrobiol inf lék 2007; 13(6): 248-252.
    6. Horning SJ, Hoppe RT, Breslin S, et al. Stanford V and radiotherapy for locally extensive and advanced Hodgkin´s disease: Mature results of a prospective clinical trial. J Clin Oncol 2002; 20(3): 630-637. Go to original source...
    7. Kodym P, Tolarová V. Návrh standardních diagnostických metodik: schémata postupů vyšetřování na toxoplasmózu. Zprávy CEM 1997; 6: 27-28.
    8. Kodym P, Tolarová V. Vyšetřování na toxoplasmózu a interpretace výsledků: komentář k návrhu standardních metodik. Zprávy CEM 1997; 6: 26-29.
    9. Masur H, Kaplan J, Holmes K. 2001 USPHS/IDSA Guidelines for the Prevention of Opportunistic Infections in Persons Infected with Human Immunodeficiency Virus. www. cdc.gov, 2001.
    10. Mechain B, Garin Y, Robert-Ganganeux F, et al. Lack of utility of specific immunoglobulin G antibody avidity for serodiagnosis of reactivated toxoplasmosis in immunocompromised patiens. Clin Diagn Lab Immun. 2000; 7: 703-705. Go to original source... Go to PubMed...
    11. Bohutová J, Štrof J, Staňková M. Postižení mozku u nemocných a HIV/AIDS v CT obraze. Čes. Radiol. 2001; 55: 351-355.
    12. Brew B. Less common complications causing spinal cord disease in advanced HIV infection. In: Brew B, ed. HIV Neurology. Oxford: Oxford University Press, Inc, 2001.
    13. Sell M, Sander B, Klingebiel R. Ventriculitis and hydrocephalus as the primary manifestation of cerebral toxoplasmosis associated with AIDS. J Neurol. 2005; 252: 234-236. Go to original source... Go to PubMed...
    14. Borges A, Figueiredo J. Evaluation of intrathecal synthesis of specific IgG antibodies against Toxoplasma gondii in the diagnosis assesment of presumptive toxoplasma encephalitis in AIDS patients. Rev Soc Bras Med Trop. 2004; 37: 480-484. Go to original source... Go to PubMed...
    15. Bartlett J, Gallant J. Medical management of HIV infection. Baltimore: John Hopkins Medicine Health Publishing Business Group, 2004.
    16. Gildenberg P, Gathe J, Kim J. Stereotactic biopsy of cerebral lesions in AIDS. Clin Infect Dis. 2000; 30: 491-499. Go to original source... Go to PubMed...

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