Onkologie. 2010:4(5):302-307

The role of radiotherapy in treatment of soft tissue sarcoma

Pavel Lovas, Zuzana Lovasová, Jana Garčicová
Klinika radiační onkologie LF MU, Masarykův onkologický ústav, Brno

Based on their experience, literature review and recommendations of international organizations, the authors provide an evidencebased

review of this issue.

Keywords: radiotherapy, interstitial brachytherapy, limb sarcoma, wide surgery

Published: December 31, 2010  Show citation

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Lovas P, Lovasová Z, Garčicová J. The role of radiotherapy in treatment of soft tissue sarcoma. Onkologie. 2010;4(5):302-307.
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    References

    1. Dušek L, Mužík J, et al. Epidemiologie zhoubných nádorů v České republice [online]. Masarykova univerzita, [2005], [cit. 2010-8-31]. Dostupný z www: http://www.svod.cz. Verze 7.0 [2007].
    2. Casal PG, Blay JY. Soft tissue sarcomas: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Annals of Oncology 2010; 21(Suppl 5): v198-v203. Go to original source... Go to PubMed...
    3. Lee B, Gottschalk AR. Soft tissue sarkoma. In: Hansen EK, Roach M III, et al. Handbook of evidence-based radiation oncology, Springer 2007: 409-416.
    4. Benjamin RS. Soft tissue sarcomas. In: Skeel RT, et al. Handbook of cancer chemotherapy, 7th edition. Lippincott Williams and Wilkins 2007: 420-432.
    5. Sobin LH, Wittekind Ch. UICC Klasifikace zhoubných novotvarů TNM, 6. vydání 2002, česká verze 2004, Wiley-Liss, New York, 93-94. Go to original source...
    6. NCCN Clinical Practice Guidelines in Oncology [online], Soft Tissue Sarcoma v.2.2010; 2010 National Comprehensive Cancer Network, [cit. 2010-09-08], dostupný www.nccn.org.
    7. Tierney JF. Adjuvant chemotherapy for localised resectable soft-tissue sarcoma of adults: Meta-analysis of individual data. Lancet 1997; 350, no. 9092: 1647-1654. Go to original source...
    8. Adjuvant chemotherapy for lokalized resectable soft tissue sarcoma in adults: sarcoma meta-analysis collaboration (SMAC). Cochrane database systematic reviews, no. 4, Article ID CD001419, 2000.
    9. Pervaiz N, Colterjohn N, et al. A systematic meta-analysis of randomised controlled trials of adjuvant chemotherapy for localised resectable soft-tissue sarcoma. Cancer 2008; 113(3): 573-581. Go to original source... Go to PubMed...
    10. Frustaci S, Gherlinzoni F, et al. Adjuvant chemotherapy for adult soft tissue sarcomas of extremities and girdles: result of the Italian randomised cooperative trial. Journal of clinical oncology 2001; 19(5): 1238-1247. Go to original source... Go to PubMed...
    11. Woll PJ, Glabbeke M, et al. Adjuvant chemotherapy with doxorubicin and ifosfamidein resected soft tissue sarcoma: interim analysis of randomised phase II trial. Journal of clinical oncology, 2007; 25: 18. ASCO annual meeting proceedings. Go to original source...
    12. Salgado R, van Marck E. Soft tissue tumors: the surgicalpathologist´s persepective, in: DeSchepper M, Vanhoemacker F, et al. Imaging of soft tissue tumors, 3rd edition, Springer 2006: 107-116. Go to original source...
    13. Enneking WF, Spanier SS, Goodman M. A system for the surgical staging of musculoskeletal sarcom. Clinical orthopaedics and related research, 1980; 153: 106-120. Go to original source...
    14. Barrett A, Dobbs J, et al. Sarcoma, IN: Practical radiotherapy planning. 4th edition, Hodder Arnold, 2009, London, 408-414. Go to original source...
    15. O´Sullivan B, Davis MA, et al. Preoperative versus postoperative radiotherapy in soft-tissue sarcoma of the limbs: a randomised trial. The Lancet 2002; 359: 2235-2240. Go to original source... Go to PubMed...
    16. Mundt AJ, Azhar A, et al. Conservative surgery and adjuvant radiation therapy in the management of adult soft tissue sarcoma of the extremities: clinical and radiobiological results. IJROBP 1995; 32(4): 977-985. Go to original source... Go to PubMed...
    17. Davis MA, O´Sullivan B, et al. Function and health status outcomes in a randomized trial comparing preoperative and postoperative radiotherapy in extremity soft tissue sarcoma. J Clin Oncol 2002; 20: 4472-4477. Go to original source... Go to PubMed...
    18. Pisters PWT, O´Sullivan B, et al. Evidence-based recommendations for local therapy for soft tissue sarcomas. J Clin Oncol 2007; 25: 1003-1008. Go to original source... Go to PubMed...
    19. White LM, Wunder JS, et al. Histologic assesmetn of peritumoral edema in soft tissue sarcoma. Int. J. Radiation Oncology Biol. Phys., 2005; 61(5): 1439-1445. Go to original source... Go to PubMed...
    20. Burnet N GTV + CTV for soft tissue sarcoma of limbs. ESTRO course, Tours, France, June 2009.
    21. Mundt AJ, Awan A, et al. Conservative surgery and adjuvant radiation therapy in the management of adult soft tissue sarcoma of the extremities: clinical and radiobiological results. Int. J. Radiation Oncology Biol. Phys. 1995; 32(4): 977-985. Go to original source... Go to PubMed...
    22. Lartigau E, Kantor G, et al. Définition des volumes cibles dans les sarcomes des tissus mous des extrémites. Cancer Radiothérapie 2001; 5(5): 696-703. Go to original source... Go to PubMed...
    23. VORTEX, UK-opened 01/02/06. A randomised phase 3 trial comparing a two-phase konventional radiotherapy treatment whit that of a single phase treatment to selectively spare normal tissue and increase limb function whitout compromising local control in soft tissue sarcomas.
    24. Stinson SF, Delaney TF, et al. Acute and long term effects on on limb funktion of combined modality therapy in patients treated with limb sparing surgrgery for soft tissue sarcoma of extremity. Int. J. Radiation Oncology Biol. Phys. 1991; 21: 1493-1499. Go to original source... Go to PubMed...
    25. Zagars GK, Ballo MT. Significance of dose in postoperative radiotherapy for soft tissue sarcoma. Int. J. Radiation Oncology Biol. Phys. 2003; 56(2): 473-481. Go to original source... Go to PubMed...
    26. Holt GE, Grifin AM Fractures following raiotherapy and limb-salvige surgery for lower extremity soft-tissues sarcomas. The journal of bone and joint surgery 2005; 87(2): 315-319. Go to original source... Go to PubMed...
    27. Cannon CP, Ballo MT, et al. Complications of combined modality treatment of primary lower extremity soft-tissue sarcomas. Cancer 2006; 107(10): 2455-2461. Go to original source... Go to PubMed...
    28. Enneking WF, Spanier SS, et al. The effect of the anatomic setting on the results of surgical procedures for soft parts sarcoma of the thigh. Cancer 1981; 47: 1005-1022. Go to original source...
    29. Lartigau E, Gerbaulet A. Soft tissue sarcomas. In: Gerbaulet A, Potter R, et al. The GEC ESTRO Handbook of brachyterapy. Estro 2002: 561-572.
    30. Habrand JL, Gerbaulet A, Pejovic MH, et al. Twenty years experience of interstitial iridium brachytherapy in the management of soft tissue sarcomas. Int J Radiat Oncol Biol Phys 1991; 20: 405-411. Go to original source... Go to PubMed...
    31. Lartigau E, Kantor G, Tarab S, et al. Definitions of target volumes in soft tissue sarcomas of the extremities. Cancer Radiother 2001; 5: 695-703. Go to original source... Go to PubMed...
    32. Petera J, Soumarova R, Ruzickova J, Neumannova R, Dusek L, Sirak I, et al. Perioperative Hyperfractionated HighDose Rate Brachytherapy for the Treatment of Soft Tissue Sarcomas: Multicentric Experience. Ann Surg Oncol 2010; 17: 206-210. Go to original source... Go to PubMed...
    33. Yang JC, Chang AE, Baker AR, et al. Randomized prospective study of the benefit of adjuvant radiation therapy in the treatment of soft tissue sarcomas of the extremity. J Clin Oncol 1998; 16: 197-203. Go to original source... Go to PubMed...

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