Onkologie. 2010:4(5):322-325
Pancreas cancer burden of the Czech population
- 1 Fakultní nemocnice, Brno
- 2 Geografický ústav Přírodovědecké fakulty Brno
Over the last 46 years, there were registered 56 828 cases of pancreatic cancer (PC; ICD-10: C25) in the Czech population with rate 19.1
per 100,000 males and 18,2 per 100,000 females in 2007. Between 1989–2005 the prevalence of PC increased by 45.9 % in males to 629,
by 119.1 % in females to 241. A total of 3,632 multiple PC registered in 1976–2005 in the Czech Cancer Registry there were 321 (1.5 %)
primary and 1 581 (7.4 %) subsequent in males, 241 (1.2 %) primary and 1 489 (7.7 %) subsequent in females, of which were 11 % multiple
PC of all new registered PC. Double PC were higher in females, multiple in males. The number of primary PC increased to 34 cases, of
subsequent to 258 in 2005. Almost half of multiple PC in males and third of females were registered in the age group of 35–64 years. Of
3.632 multiple PC were distributed mostly in the Northern 11.8 % and Southern 11.1 % Moravia regions and in Prague 8.1 %. The average
interval between primary PC and subsequent other neoplasms (ICD-10: C00–D48) was 3.2 years in males and 2.1 years in females, the
ratio of synchronous to metachronous cases was 1:0.7 in males and 1:0.5 in females. The most frequent cases following primary PC in
males were cancers of digestive, respiratory, urinary and genital tract, in females these were cancers of digestive, genital and urinary
tract and breast. The most frequent cancers preceding the next subsequent PC included in males primary cancers of the skin, digestive,
respiratory, urinary and genital tract, in females cancers of the skin, genital and digestive tract and breast. Up to October 2007, of 562
primary PC died 526 (93.6 %) patients and survived only 23 males and 13 females. The Czech screening programme and medical surveillance
is decisive in view of risk of multiple PC and digestive, especially colorectal cancers. The analysis of 165,050 subsequent neoplasms
in 125,262 cancer patients continue with ongoing issues.
Keywords: cancer of pancreas, incidence, prevalence, multiple malignant neoplasms, primary and subsequent cancers
Published: December 31, 2010 Show citation
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