Onkologie. 2013:7(6):292-295

Mandibular angiosarcoma

Richard Pink¹, Patrik Flodr², Peter Tvrdý¹, Jindřich Pazdera¹

¹ Klinika ústní, čelistní a obličejové chirurgie FN a LF UP Olomouc

² Ústav patologie LF UP Olomouc

Introduction: Malignant mesenchymal tumours of the orofacial region are extremely rare and comprise only 1% of all malignant orofacial

tumours with more than 50 subtypes. Angiosarcomas are highly malignant neoplasms that originate from blood or lymphatic vessels.

Angiosarcomas form 5,4 % of all sarcomas and in the head and neck region are the most frequent type of sarcoma.

Aim: The aim of this case report is to describe a rare malignant neoplasm in the head and neck topography which can be diagnostic

difficulty and may be missed or unrecognised with fatal consequences for the patient.

Materials, methods, results: The authors describe the clinical manifestations of the disease, the diagnosis and therapy of mandibular

angiosarcoma in a seriously ill patient. The diagnosis was made on the basis of the histopathological findings and immunohistochemistry.

The following treatment was radical surgery with subsequent radiotherapy and 18 months later, the 84 year old female patient

remains alive and apparently healthy.

Conclusions: Angiosarcoma has currently been literary described only in small number of patients. Guidelines for optimal treatment

are still unknown and the average survival is one year and a half.

Keywords: mesenchymal tumours, angiosarcoma, orofacial tumours

Published: December 1, 2013  Show citation