Onkologie. 2015:9(5):214-217

Complex therapy of brain glioma

Pavel Fadrus¹, Pavel Šlampa², Radek Lakomý³, Martin Smrčka¹

¹ Neurochirurgická klinika, FN Brno &ndash, Bohunice a LF MU, Brno

² Klinika radiační onkologie, Masarykův onkologický ústav, Brno

³ Klinika komplexní onkologické péče, Masarykův onkologický ústav, Brno

Glioma is a common type of primary brain intraaxial tumors. This is a broad group of tumors that differ in their typical localization,

age predisposition, morphology, degree of malignancy and the tendency to progression. On the basis of the WHO classification with

grading system are divided into two basic groups: glioma low grade malignancy (low grade glioma – LGG) and glioma high grade of

malignancy (high grade glioma – HGG). These two groups in between vary considerably in their biological characteristics and thus the

overall prognosis of the patient. Among the basic capabilities of their therapies include surgical resection followed by radiation therapy

and chemotherapy. In the article are analyzed the possibilities and limitations of these various modalities of treatment for LGG and HGG.

Keywords: brain glioma, surgical resection, radiation therapy, chemotherapy

Published: December 1, 2015  Show citation