Onkologie. 2015:9(6):264-267

Advanced pancreatic cancer

Miroslav Ryska^1,4, Hana Parobková², Pavel Záruba¹, Luboš Petruželka³

¹ Chirurgická klinika 2. LF UK a ÚVN, Praha

² Radiodiagnostické oddělení ÚVN &ndash, VFN, Praha

³ Onkologická klinika 1. LF UK a ÚVN, Praha

⁴ Fakulta zdravotníctva a sociálnej práce, Trnavská Univerzita, Trnava

Pancreatic cancer is a solid, malignant, unpreventable, chemoradioresistant tumour with an unfavourable prognosis. Radical resection

is the only potentially curable treatment modality that, coupled with adjuvant chemotherapy, significantly prolongs the survival in

20% of patients. In a proportion of primary unresectable patients (borderline), an active approach is currently preferred that utilizes

neoadjuvant chemo(radio)therapy in order to reach subsequent resection. In approximately 70% of patients, palliative or symptomatic

treatment is indicated. When pancreatic cancer is suspected, it is necessary to refer the patient as soon as possible to a specialized centre.

The prevailing feeling of despair in a part of the professional public has to be replaced by a rational approach.

Keywords: pancreatic cancer, staging, borderline, radical resection

Published: December 1, 2015  Show citation