Onkologie. 2023:17(3):169-174 | DOI: 10.36290/xon.2023.034

Breast cancer and pregnancy

Marta Krásenská
Klinika komplexní onkologické péče, Masarykův onkologický ústav, Brno

The coincidence of breast cancer and pregnancy is increasing due to the postponement of childbearing until later in life. This article describes the newly proposed division into breast cancer in pregnancy and breast cancer in the postpartum period, which differ in biological characteristics and prognosis. Pregnancy after treatment for breast cancer has long been considered inappropriate, especially in patients with hormone-dependent forms of the disease (luminal carcinomas). However, the available data show that pregnancy in women in remission after treatment for breast cancer is possible and safe, even with the use of assisted reproductive techniques.

Keywords: pregnancy-associtated breast cancer, postpartum breast cancer, pregnancy following breast cancer, assisted reproductive technology, young women.

Accepted: June 12, 2023; Published: June 16, 2023  Show citation

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Krásenská M. Breast cancer and pregnancy. Onkologie. 2023;17(3):169-174. doi: 10.36290/xon.2023.034.
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    References

    1. Peccatori FA, Azim HA, Orechhia R, et al. Cancer, pregnancy and fertility: ESMO clinical practice guidelines for diagnosis, treratment and follow-up. Ann Oncol. 2013;24 (suppl 6):160-170. Go to original source... Go to PubMed...
    2. Parazzini F, Franchi M, Tavani A, et al. Frequency of pregnancy related cancer. Int J Gynecol Cancer. 2017;27(3):613-619. Go to original source... Go to PubMed...
    3. Novotvary 2018 - Současné epidemiologické trendy novotvarů v České republice. Zhoubný novotvar prsu (C50) u žen. Available from: https://www.uzis.cz/res/f/008352/novotvary2018.pdf.
    4. Matthews TJ, Hamilton BE. Delayed childbearing: more women are having their first child later in life. NCHS Data Brief. 2009;1-8. Go to original source...
    5. Lefrère H, Lenaerts L, Borges VF, et al. Postpartum breast cancer: mechanisms underlying its worse prognosis, treatment implications, and fertility preservation. Int J Gynecol Cancer. 2021;31:412-422. Go to original source... Go to PubMed...
    6. Amant F, Lefrère H, Borges VF, et al. The definition of pregnancy-associated breast cancer is outdated and should no longer be used. Lancet Oncol. 2021;22:753-754. Go to original source... Go to PubMed...
    7. Amant F, von Minckwitz G, Han SN, et al. Prognosis of women with primary breast cancer diagnosed during pregnancy: results from an international collaborative study. J Clin Oncol. 2013;31:2532-2539. Go to original source... Go to PubMed...
    8. Azim HA Jr, Santoro L, Russell-Edu W, et al. Prognosis of pregnancy-associated breast cancer: A meta-analysis of 30 studies. Cancer Treat Rev. 2012;38:834-842. Go to original source... Go to PubMed...
    9. Lyons T, Schedin P, Borges V. Pregnancy and breast cancer: when they collide. J Mammary Gland Biol Neoplasia. 2009;14:87-98. Go to original source... Go to PubMed...
    10. Loibl S, Han SN, von Minckwitz G, et al. Treatment of breast cancer during pregnancy: an observational study. Lancet Oncol. 2012;13:887-896. Go to original source... Go to PubMed...
    11. Peccatori FA, Lambertini M, Scarfone G, et al. Biology, staging, and treatment of breast cancer during pregnancy: reassessing the evidences. Cancer Biol Med. 2018. doi: 10.20892/j.issn.2095-3941.2017.0146. Go to original source... Go to PubMed...
    12. Boere I, Lok Ch, Poortmans P, et al. Breast cancer during pregnancy: epidemiology, phenotypes, presentation during pregnancy and therapeutic modalities. Best Practice and Research Clinical Obsterics and Gynaecology. 2022;82:46-59. Go to original source... Go to PubMed...
    13. Loibl S, Schmidt A, Gentillini O, et al. Breast cancer diagnosed during pregnancy adapting recent advances in breast cancer care for pregnant patients. JAMA Oncology. 2015;1(8):1145-1153. Go to original source... Go to PubMed...
    14. Shachar SS, Gallagher K, McGuire K, et al. Multidisciplinary management of breast cancer during pregnancy. The Oncologisst. 2017;22:324-334. Go to original source... Go to PubMed...
    15. Callihan EB, Gao D, Jindal S, et al. Postpartum diagnosis demonstrates a high risk for metastasis and merits an expanded definition of pregnancy-assotiated breast cancer. Breast Cancer Res Treatt. 2013;138:549-559. Go to original source... Go to PubMed...
    16. Munguía MU, Esparza SL, Stern D. Breastfeeding duration and the risk of all-cause and breast cancer mortality among parous women from the Mexican teachers´cohort. J Glob Oncol. 2018;4:1-27. Go to original source...
    17. Steinheim H, Møller B, van Dijk T, et al. Cause specific survival for women diagnosed with cancer during pregnancy or lactation: a registry-based cohort study. J Clin Oncol. 2009;27:45-51. Go to original source... Go to PubMed...
    18. Partridge AH, Niman SM, Ruggeri M, et al. Interrupting endocrine therapy to attempt pregnancy after breast cancer. N Engl J Med. 2023;388:1645-1656. Go to original source... Go to PubMed...
    19. Goldrat O, Kroman N, Peccatori FA, et al. Pregnancy following breast cancer using assisted reproduction and its effect on long-term outcome. Eur J Cancer. 2015;51:1490-1496. Go to original source... Go to PubMed...
    20. Lambertini M, Blondeaux E, Bruzzone M, et al. Pregnancy after breast cancer: A systematic review and meta-analysis. J Clin Oncol. 2021;39:3293-3305. Go to original source... Go to PubMed...
    21. Lambertini M, Ameye L, Hamy AS, et al. Pregnancy after breast cancer in patients with gemline BRCA mutations. J Clin Oncol. 2020;38:3012-3023. Go to original source... Go to PubMed...

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