Onkologie. 2017:11(3):128-133 | DOI: 10.36290/xon.2017.025

NonHodgkin lymphomas in elderly patients

Andrea Janíková

Interní hematologická a onkologická klinika FN Brno a LF MU Brno

An aging of population is coupled with an age-associated increase in incidence of NonHodgkin lymphomas (NHL), which will

lead to a greater need for management in the elderly (>65 years) as well as very elderly ( >80 years) individuals. Elderly patients

represent a subgroup with higher treatment difficulties, because of comorbidities and smaller spectrum of treatment choice.

Elderly patients (> 80 years) are only rarely included in the clinical trials. There is considerable improvement in clinical outcome

in the NHL management over the last two decades, caused by introduction of monoclonal antibodies and intensive initial therapy.

On the other hand, little is known of the effectiveness of standard and also alternative therapy options for older patients. In

this review, we summarize the available data from the global perspective, and select results from clinical studies to make basic

treatment recommendations.

Keywords: lymphomas, NHL, elderly patients, aging

Published: June 1, 2017  Show citation