Onkologie. 2018:12(3):130-138 | DOI: 10.36290/xon.2018.025

CyberKnife in treatment brain metastases

Štefan Reguli1, Jakub Cvek2, Radim Lipina1, Jan Krajča3, Natálie Stieberová2, Přemysl Dobeš2, Lukáš Knybel2
1 Neurochirurgická klinika, FN Ostrava
2 Onkologická klinika, FN Ostrava
3 Radiodiagnostický ústav, FN Ostrava

Brain metastases are an important and frequently treated indication in modern radiosurgery. This non-invasive method offersgood local control with minimum toxicity and repeability of treatment. The CyberKnife is a device for frameless whole-bodyradiosurgery using image guided robotic technology and linear accelerator as a photon source. In our prospective study wemeasure the volume of brain metastases on MRI with use of computer-assisted volumetry and we evaluate the predictive valueof these volumetric changes. We track the effect of therapy according to histological type of tumor, number of brain metastases,sex and initial performance status of patients. The group of patients with CyberKnife treateted brain metastases, that is uniquein our conditions, is then statistically analyzed and results are compared to peer-reviewed articles of institutions using the sametechnology and reference data from frame-based (Gamma Knife) radiosurgery centers are matched.

Keywords: brain metastasis, stereotactic radiosurgery, CyberKnife, volumetry

Published: June 1, 2018  Show citation

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Reguli Š, Cvek J, Lipina R, Krajča J, Stieberová N, Dobeš P, Knybel L. CyberKnife in treatment brain metastases. Onkologie. 2018;12(3):130-138. doi: 10.36290/xon.2018.025.
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