Onkologie. 2019:13(3):123-128 | DOI: 10.36290/xon.2019.024

Diagnosis, surgery and systemic treatment of brain metastases

Tomáš Kazda1,2,3, Radek Lakomý4,5, Petr Pospíšil1,2, Ludmila Hynková1,2, Jiří Šána3,4,5, Pavel Fadrus6,, Radim Jančálek7,8, Robert Bartoš9,10, Renata Belanová8,11, Ondřej Slabý3,4,5, Pavel Šlampa1,2
1 Klinika radiační onkologie, Masarykův onkologický ústav, Brno
2 Klinika radiační onkologie, Lékařská fakulta Masarykovy Univerzity, Brno
3 CEITEC – Středoevropský technologický institut, Masarykova Univerzita, Brno
4 Klinika komplexní onkologické péče, Masarykův onkologický ústav, Brno
5 Klinika komplexní onkologické péče, Lékařská fakulta Masarykovy Univerzity, Brno
6 Neurochirurgická klinika, Fakultní nemocnice Brno, Brno
7 Neurochirurgická klinika, Fakultní nemocnice u sv. Anny v Brně, Brno
8 Lékařská fakulta Masarykovy Univerzity, Brno
9 Neurochirurgická klinika Univerzity J. E. Purkyně, Masarykova nemocnice, KZ a. s., Ústí nad Labem
10 Anatomický ústav 1. LF UK, Praha
11 Oddělení radiologie, Masarykův onkologický ústav, Brno

Secondary brain tumors, brain metastases, develop in up to 30–40% of all solid tumor cancer patients, with increasing incidence. The aim of this review is to provide both basic as well as current information on up-to-date treatment options for patients with brain metastases except of radiotherapy, which is discussed in separate, company review. The aim is, in accordance with the focus of the journal, to provide didactical and practical information on the issue of secondary brain tumors with an emphasis on their usefulness in daily clinical practice. With increasing therapeutic options, including surgery and advanced targeted therapy and immunotherapy, a more personalized approach to the treatment of this disease can be expected in the future.

Keywords: brain metastases, neurosurgery, targeted therapy, imunotherapy

Published: May 24, 2019  Show citation

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Kazda T, Lakomý R, Pospíšil P, Hynková L, Šána J, Fadrus P, et al.. Diagnosis, surgery and systemic treatment of brain metastases. Onkologie. 2019;13(3):123-128. doi: 10.36290/xon.2019.024.
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