Onkologie. 2020:14(3):126-130 | DOI: 10.36290/xon.2020.025

Current perspective on the treatment of advanced/metastatic colorectal cancer

Stanislav John

Klinika onkologie a radioterapie, FN Hradec Králové

Ústav lékařské biologie a genetiky, LF UK v Hradci Králové

Metastatic spread is responsible for the majority of all cancer deaths (1). The same, unfortunately, applies to colorectal cancer (CRC). However, multimodal combination therapy significantly improves the prognosis of patients, with some even being able to achieve long-term disease remission or even complete cure. More readily available and more accurate molecular analyses should be helpful in the effort to establish diagnosis, prognosis, and appropriate therapeutic objectives for a strictly individualized treatment. Novel treatment strategies emerge from clinical trials, but the rates of their implementation vary across countries. The present text aims at summarizing certain current recommendations while also providing some insight into the near, and hopefully more promising, future of the treatment of metastatic CRC (mCRC).

Keywords: colorectal cancer, targeted therapy.

Published: June 2, 2020  Show citation