Onkologie. 2021:15(5):231-237 | DOI: 10.36290/xon.2021.044

Surgical treatment of brain metastases

Miloš Duba^{1, 2}, Ivana Rošková^{1, 2}, Andrej Mrlian^{1, 2}, Pavel Fadrus^{1, 2}, Václav Vybíhal^{1, 2}, Tomáš Kazda³, Dagmar Al Tukmachi⁴, Jiří Šána⁴, Ondřej Hrdý^{5, 6}, Jaroslav Duba^{5, 6}, Martin Smrčka^{1, 2}

¹ Neurochirurgická klinika, FN Brno

² Neurochirurgická klinika, Lékařská fakulta Masarykovy univerzity, Brno

³ Klinika radiační onkologie, Masarykův onkologický ústav Brno

⁴ Středoevropský technologický institut, Masarykova univerzita, Brno

⁵ Klinika anestezie, resuscitace a intenzivní medicíny, FN Brno

⁶ Klinika anestezie, resuscitace a intenzivní medicíny, Lékařská fakulta Masarykovy univerzity, Brno

With an annual incidence of 5/100,000, meningioma is the most common primary intracranial extraaxial tumor. It is usually a slow-growing tumor growing from arachnoid cells. In adults, they make up approximately 30% of all intracranial tumors. They are rare in children. Meningiomas occurs significantly more common in women. Most of the tumors are benign. The clinical manifestation depends on the location and size of the tumor. In therapy, surgical treatment is most important, the aim is total removal of the tumor, which often means a complete cure of the patient. The patient's prognosis is determined by the anatomical location, radicality of the resection and the histological type of the tumor according to the WHO classification. Some meningiomas, especially skull base meningiomas, which often compress or overgrow large vessels and cranial nerves, and infiltratively growing meningiomas, which often correspond to a histologically higher grade according to the WHO classification, are very difficult to remove. An important factor in the treatment of meningiomas is also the general condition and internal comorbidities of the patients. Another treatment modality is radiosurgery. Hormone therapy remains a rather experimental alternative.

Keywords: meningioma, incidence, diagnostics, surgical therapy, dispensarization.

Published: October 11, 2021  Show citation