Onkologie. 2022:16(2):91-94 | DOI: 10.36290/xon.2022.018

Therapeutic possibilities of selected gastrointestinal complications in oncology patients

Kateřina Šašková
Onkologická klinika, FN Motol v Praze

Nausea, vomitus, diarrhea and constipation rank among the most frequent gastrointestinal complications in oncology patients. It is necessary to prevent nausea and vomitus before the therapy administration. Convenient antiemetics are chosen depending on emetogenic potential of ongoing therapeutic regimen. Main trouble in diarrhea treatment is its various etiology, even sometimes the etiology is multifactorial. Therefore it is very important to make a good differential diagnosis and to focus on patient´s anamnesis: past surgeries, ongoing therapy and patient´s regimen and diet. Constipation in oncology patient is very commonly caused by his medication, which is difficult to replace. Therefore laxatives become the part of the patient´s regular farmacotherapy. Key words: constipation, diarrhea, gastrointestinal complications, nausea, vomiting.

Keywords: gastrointestinální obtíže, nauzea, průjem, zácpa, zvracení.

Published: March 25, 2022  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Šašková K. Therapeutic possibilities of selected gastrointestinal complications in oncology patients. Onkologie. 2022;16(2):91-94. doi: 10.36290/xon.2022.018.
Download citation

References

  1. National Comprehensive Cancer Network. Antiemesis (Verze 1.2022). [online] 2019, 2022 [cit. 2022-02-24]. Dostupné z: http://www.nccn.org/professionals/physician_gls/pdf/bone.pdf.
  2. Lukáš K. Průjem. Med. Praxi. 2006;3:106-110. [cit. 13.2.2022]. Available from https://www.medicinapropraxi.cz/pdfs/med/2006/03/01.pdf.
  3. Vokurka S. Postižení dutiny ústní a trávicího traktu onkologických pacientů. Praha: Current Media; 2016.
  4. Stein A, Voigt W, Jordan K. Review: Chemotherapy-induced diarrhea. Therapeutic Advances in Medical Oncology [online]. 2010;2(1):51-63 [cit. 2022-02-17]. Available from doi:10.1177/1758834009355164. Go to original source... Go to PubMed...
  5. Gil J, Sasiadek MM. Gilbert syndrome: the UGT1A1*28 promoter polymorphism as a biomarker of multifactorial diseases and drug metabolism. Biomark Med[online]. 2012;6(2):223-230[cit. 2022-02-17]. Available from doi: 10.2217/bmm.12.4. Go to original source... Go to PubMed...
  6. UpToDate. [online]. Available from https://www.uptodate.com/contents/management-of-acute-chemotherapy-related-diarrhea.
  7. Palmer KR, Corbett CL, Holdsworth CD. Double-blind cross-over study comparing loperamide codeine and diphenoxylate in the treatment of chronic diarrhea. Gastroenterology. [online]. 1980;79(6):1272-1275 [cit. 2022-02-17]. Available from doi:10.1016/0016-5085(80)90924-5. Go to original source...
  8. Ahmed M. Checkpoint inhibitors: What gastroenterologists need to know. World Journal of Gastroenterology [online]. 2018;24(48):5433-5438 [cit. 2022-02-20]. Available from doi:10.3748/wjg.v24.i48.5433. Go to original source... Go to PubMed...
  9. National cancer institute (U.S.). Common terminology criteria for adverse events: (CTCAE). [online] 2010 [cit. 2022-02-24]. Available from http://evs.nci.nih.gov/ftp1/CTCAE/CTCAE_4.03_2010-06-14_QuickReference_5x7.pdf.
  10. Van Beek AP, Emous M, Laville M, Tack J. Dumping syndrome after esophageal, gastric or bariatric surgery: pathophysiology, diagnosis, and management. Obesity Reviews [online]. 2017;18(1):68-85 [cit. 2022-02-17]. Available from doi:10.1111/obr.12467. Go to original source... Go to PubMed...
  11. Dítě P, Bojková M, Šímová J, Kianička B, Kapounková K, Hrabovský V. Nejen nemoci pankreatu a jejich terapie pankreatickými enzymy. Interní Med. 2015;17(5):227-229.
  12. Pusceddu S, Rosii RE, Torchio M, et al. Differential Diagnosis and Management of Diarrhea in Patients with Neuroendocrine Tumors. Journal of Clinical Medicine [online]. 2020;9(8) [cit. 2022-02-19]. Avaible from doi:10.3390/jcm9082468. Go to original source... Go to PubMed...
  13. Stebel R, Vojtilová L, Husa P. Clostridium difficile Infection: an update on treatment and prevention. Vnitřní lékařství [online]. 2020;66(2):e24-e28 [cit. 2022-02-20]. Avaible from doi:10.36290/vnl.2020.037. Go to original source...
  14. Tachecí I. Zácpa a její léčba v ordinaci praktického lékaře. Med. praxi. 2013;10(6-7):231-233.
  15. Larkin PJ, Cherny NI, La Carpia D, Guglielmo M, Ostgathe C, Scotté F, Ripamonti CI. Diagnosis, assessment and mana­gement of constipation in advanced cancer: ESMO Clinical Practice Guidelines. Annals of Oncology [online]. 2018;29: iv111-iv125 [cit. 2022-02-20]. Avaible from doi:10.1093/annonc/mdy148. Go to original source... Go to PubMed...
  16. McQuade RM, Stojanovska V, Abalo R, Bornstein JC, Nurgali K. Chemotherapy-Induced Constipation and Diarrhea: Pathophysiology, Current and Emerging Treatments. Frontiers in Pharmacology [online]. 2016;7 [cit. 2022-02-20]. Avaible from doi:10.3389/fphar.2016.00414. Go to original source... Go to PubMed...
  17. Sochor M. Management vybraných symptomů v onkologické paliativní péči. Zácpa a průjem. Remedia. 2017;27:569-575 [online]. Avaible from http://www.remedia.cz/Okruhy-temat/Onkologie/Management-vybranych-symptomu-v-onkologicke-paliativni-peci/8-1h-2rQ.magarticle.aspx.




Oncology

Madam, Sir,
please be aware that the website on which you intend to enter, not the general public because it contains technical information about medicines, including advertisements relating to medicinal products. This information and communication professionals are solely under §2 of the Act n.40/1995 Coll. Is active persons authorized to prescribe or supply (hereinafter expert).
Take note that if you are not an expert, you run the risk of danger to their health or the health of other persons, if you the obtained information improperly understood or interpreted, and especially advertising which may be part of this site, or whether you used it for self-diagnosis or medical treatment, whether in relation to each other in person or in relation to others.

I declare:

  1. that I have met the above instruction
  2. I'm an expert within the meaning of the Act n.40/1995 Coll. the regulation of advertising, as amended, and I am aware of the risks that would be a person other than the expert input to these sites exhibited


No

Yes

If your statement is not true, please be aware
that brings the risk of danger to their health or the health of others.