Onkologie. 2025:19(3):165-168 | DOI: 10.36290/xon.2025.032

Compensation for interruption of radiotherapy in a patient with oropharyngeal cancer

Zdeňka Pechačová1, Radka Lohynská2, Tereza Drbohlavová1
1 Ústav radiační onkologie 1. LF UK a Fakultní nemocnice Bulovka, Praha
2 Onkologická klinika 1. LF UK a Fakultní Thomayerovy nemocnice, Praha

In squamous cell carcinomas, radiotherapy is often the primary treatment modality and prolonging the overall radiotherapy treatment time may lead to inferior treatment outcomes. Therefore, to achieve maximum benefit for patients, it is essential to apply recommended practices to compensate for interruptions in the radiation series. This case report describes the management of a prolonged pause in treatment in a patient with advanced oropharyngeal cancer and complications from multiple comorbidities.

Keywords: radiation therapy, time factors, treatment effectiveness.

Accepted: June 26, 2025; Published: July 4, 2025  Show citation

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Pechačová Z, Lohynská R, Drbohlavová T. Compensation for interruption of radiotherapy in a patient with oropharyngeal cancer. Onkologie. 2025;19(3):165-168. doi: 10.36290/xon.2025.032.
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References

  1. . Šlampa P, et al. Radiační onkologie. Praha: Maxdorf; 2021.
  2. . Modrá kniha České onkologické společnosti, 31. aktualizace. Brno: Masarykův onkologický ústav; 2025.
  3. . Lohynská R, Jirkovská M, Krátká Z. Časový faktor v radikální radioterapii nádorů hlavy a krku. Postgraduální medicína. 2020;2:115-120.
  4. . Lohynská R. Časový faktor v radikální radioterapii nádorů hlavy a krku. Dizertační práce, 2. lékařská fakulta Univerzity Karlovy. Praha; 2007.
  5. . Gonzalez Ferreira JA, Jaen Olasolo J, Azinovic I, et al. Effect of radiotherapy delay in overall treatment time on local control and survival in head and neck cancer: Review of the literature. Reports Pract Oncol Radiother J Gt Cancer Cent Pozn Polish Soc Radiat Oncol. 2015;20(5):328-339. Go to original source... Go to PubMed...
  6. . Joiner MC, van der Kogel A. Basic clinical radiobiology. 5th edition. CRC, London: Press/Taylor&Francis Group; 2019. Go to original source...
  7. . Overgaard J, Hansen HS, Specht L, et al. Five compared with six fractions per week of conventional radiotherapy of squamous-cell carcinoma of head and neck: DAHANCA 6,7 randomized controlled trial. Lancet. 2003;362:933-939. Go to original source... Go to PubMed...
  8. . Royal College of Radiologist: The timely delivery of radical radiotherapy guidelines for the management of unscheduled treatment interruptions, 4th edition, January 2019. Available from: https://www.rcr.ac.uk.
  9. . Pechačová Z, Lohynská R. Klinická aplikace principů časového faktoru v radioterapii při kompenzaci přerušení ozařovací série. Klin Onkol. 2021;34(6):455-462. Go to original source... Go to PubMed...
  10. . Lohynska R, Jirkovska M, Novakova-Jiresova A, et al. Determining priority risk groups for compensation of treatment breaks in radical radiotherapy in patients with locally advanced head and neck cancer. J BUON. 2021;26(3):792-801.
  11. . Lohynska R, Jirkovska M, Malinova B, et al. Tumour volume and radiotherapy prolongation in locally advanced head and neck cancer patients treated with radical IMRT. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2022;166(4):405-411. Go to original source... Go to PubMed...




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