Onkologie. 2026:20(3):176-180 | DOI: 10.36290/xon.2026.032

Malignant phyllodes tumor of the breast: clinical case and review of the literature

Zuzana Bielčiková^{1, 2}, Barbora Englcová³, David Erhart^3*

¹ Onkologická klinika, Všeobecná fakultní nemocnice a 1. Lékařská fakulta Univerzity Karlovy v Praze

² Onkologická ambulance, Nemocnice na Františku, Praha

³ Chirurgické oddělení, Nemocnice na Františku, Praha

^*V době sepisování publikace

Malignant phyllodes tumor (MPT) of the breast is a rare entity, typically characterized by an aggressive clinical course with rapid tumor growth. Surgery remains the only treatment modality firmly established in current therapeutic recommendations; however, achieving adequate surgical margins may be challenging in many cases. Neither adjuvant radiotherapy nor chemotherapy has been shown to improve overall survival, and their use is largely based on retrospective data. This article presents several case reports and summarizes the current knowledge regarding malignant phyllodes tumors and their management.

Keywords: fibroepithelial tumors, breast tumors, phyllodes tumor, malignant phyllodes tumor.

Accepted: June 15, 2026; Published: July 1, 2026  Show citation