Onkologie. 2009:3(3):181-189

Subsequent primary neoplasms in 125 262 cancer patients in the Czech Republic 1976-2005

Edvard Geryk², Petr Dítě^1,2, Miloš Pešek³, Jiří Kozel⁴

¹ III. interní klinika gastroenterologická, FN Brno-Bohunice

² Fakultní nemocnice Brno Bohunice

³ Fakultní nemocnice Plzeň

⁴ PřF MU Brno

During 1976–2005 the Czech Cancer Registry registered 1.486,984 neoplasms dg. C00–D48, of which in 125,262 (8.4 %) cancer patients

were diagnosed 165,050 (11.1 %) subsequent neoplasms. There were treated 81.7 % patients of duplicities and 18.3 % of multiplicities. There

were higher duplicities in women and on the contrary higher multiplicities in men. The age groups 50–69 years contributed most to 52.4 %

primary diseases in men and 47.8 % in women. Their most frequent occurence were in regions Northern and Southern Moravia and Prague.

The most frequent of primary diseases were tumors of skin 42.8 %, digestive 11.8 %, urinary 6.8 % and respiratory system 4.8 %, breast

8.4 %, female 7 % and male genital tract 4.2 %. The average length between the primary and subsequent diseases was 6 years in men and

6.6 years in women. During the first year after primary disease occured 15,602 (17.4 %) subsequent neoplasms in men and 11,689 (15.5 %)

in women. The proportion of synchronous and metachronous diseases was 1:4.8 in men and 1:5.4 in women. From 125,262 patients died

84,101 (29.9 % men, 27.9 % women) and survived 41,161 (12.2 % men, 16.5 % women) as of 17. 10. 2007. The numbers of died from primary

neoplasms increased till 1994–1995 and survived till 2002, then decreased. From the presented data follows the necessity of screening

programmes and importace of sufficient long permanent medical surveillance, especially in view of multiple primary and subsequent solid

tumors and the most frequent cancers of skin. The broad public information and education of the first cancer symptoms and improving of

life-style is not yet sufficient both for healthy population and for 395,547 treated patients with cancers in 2005.

Keywords: multiple neoplasms, time, age and space distribution.

Published: June 15, 2009  Show citation