Onkologie. 2010:4(2):72-74

Radical prostatectomy

Michal Grepl
Urologická klinika FN a LF UP Olomouc

Prostate cancer is one of the most common malignancies in men. The number of surgeries required increases with the increasing numbers of

prostate cancers diagnosed. Radical prostatectomy is the method of choice for localized prostate cancer. It is the only therapeutic approach

the benefit of which was confirmed in a randomized prospective trial. When performed by an experienced surgeon, it results in excellent

oncological as well as functional outcomes and minimal complications. Currently, there is no clear evidence of the superiority of one surgical

approach over another. The role of radical prostatectomy and pelvic lymphadenectomy in advanced disease is yet to be determined.

Keywords: prostate cancer, radical prostatectomy

Published: May 1, 2010  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Grepl M. Radical prostatectomy. Onkologie. 2010;4(2):72-74.
Download citation

References

  1. Young H. Radical perineal prostatectomy. Johns Hopkins Hosp Bull 1905; 16: 315-321.
  2. Memmelaar J, Millin T. Total prostatovesiculectomy; retropubic approach. J Urol 1949; 62(3): 340-348. Go to original source... Go to PubMed...
  3. Walsh PC, Donker PJ. Impotence following radical prostatectomy: insight into etiology and prevention. J Urol 1982; 128(3): 492-497. Go to original source... Go to PubMed...
  4. Bill-Axelson A, Holmberg L, Filén F, Ruutu M, Garmo H, Busch C, Nordling S, Häggman M, Andersson SO, Bratell S, Sp?ngberg A, Palmgren J, Adami HO, Johansson JE; Scandinavian Prostate Cancer Group Study Number 4. Radical prostatectomy versus watchful waiting in localized prostate cancer: the Scandinavian prostate cancer group-4 randomized trial. J Natl Cancer Inst. 2008; 100(16): 1144-1154. Go to original source... Go to PubMed...
  5. Ficarra V, Novara G, Artibani W, Cestari A, Galfano A, Graefen M, Guazzoni G, Guillonneau B, Menon M, Montorsi F, Patel V, Rassweiler J, Van Poppel H. Retropubic, laparoscopic, and robot-assisted radical prostatectomy: a systematic review and cumulative analysis of comparative studies. Eur Urol. 2009; 55(5): 1037-1063. Epub 2009 Jan 25. Go to original source... Go to PubMed...
  6. Potosky AL, Warren JL. Radical prostatectomy: does higher volume lead to better quality? J Natl Cancer Inst 1999; 91(22): 1906-1907. Go to original source... Go to PubMed...
  7. Lepor H, Nieder AM, Ferrandino MN. Intraoperative and postoperative complications of radical retropubic prostatectomy in a consecutive series of 1,000 cases. J Urol 2001; 166(5): 1729-1733. Go to original source...
  8. Augustin H, Hammerer P, Graefen M, Palisaar J, Noldus J, Fernandez S, Huland H. Intraoperative and perioperative morbidity of contemporary radical retropubic prostatectomy in a consecutive series of 1 243 patients: results of a single center between 1999 and 2002. Eur Urol 2003; 43(2): 113-118.
  9. Maffezzini M, Seveso M, Taverna G, Giusti G, Benetti A, Graziotti P. Evaluation of complications and results in a contemporary series of 300 consecutive radical retropubic prostatectomies with the anatomic approach at a single institution. Urology 2003; 61(5): 982-986. Go to original source... Go to PubMed...
  10. D'Amico AV, Whittington R, Malkowicz SB, Schultz D, Blank K, Broderick GA, Tomaszewski JE, Renshaw AA, Kaplan I, Beard CJ, Wein A. Biochemical outcome after radical prostatectomy, external beam radiation therapy, or interstitial radiation therapy for clinically localized prostate cancer. JAMA 1998; 280(11): 969-974. Go to original source... Go to PubMed...
  11. Corral DA, Bahnson RR. Survival of men with clinically localized prostate cancer detected in the eighth decade of life. J Urol 1994; 151(5): 1326-1329. Go to original source... Go to PubMed...
  12. Makarov DV, Trock BJ, Humphreys EB, Mangold LA, Walsh PC, Epstein JI, Partin AW. Updated nomogram to predict pathologic stage of prostate cancer given prostate-specific antigen level, clinical stage, and biopsy Gleason score (Partin tables) based on cases from 2000 to 2005. Urology 2007; 69(6): 1095-1101. Go to original source... Go to PubMed...
  13. Costello AJ, Brooks M, Cole OJ. Anatomical studies of the neurovascular bundle and cavernosal nerves. BJU Int 2004; 94: 1071. Go to original source... Go to PubMed...
  14. Sofer M, Hamilton-Nelson KL, Schlesselman JJ, Soloway MS. Risk of positive margins and biochemical recurrence in relation to nerve-sparing radical prostatectomy. J Clin Oncol 2002; 20: 1853. Go to original source... Go to PubMed...
  15. Ward JF, Zincke H, Bergstralh EJ, et al. The impact of surgical approach (nerve bundle preservation versus wide local excision) on surgical margins and biochemical recurrence following radical prostatectomy. J Urol 2004; 172: 1328. Go to original source... Go to PubMed...
  16. Ogura K, Maekawa S, Okubo K, et al. Dynamic endorectal magnetic resonance imaging for local staging and detection of neurovascular bundle involvement of prostate cancer: correlation with histopathologic results. Urology 2001; 57: 721. Go to original source... Go to PubMed...
  17. Hricak H, Wang L, Wei DC, et al. The role of preoperative endorectal magnetic resonance imaging in the decision regarding whether to preserve or resect neurovascular bundles during radical retropubic prostatectomy. Cancer 2004; 100: 2655. Go to original source... Go to PubMed...
  18. Epstein JI, Pizov G, Walsh PC. Correlation of pathologic findings with progression after radical retropubic prostatectomy. Cancer 1993; 71: 3582. Go to original source...
  19. Rosen MA, Goldstone L, Lapin S, et al. Frequency and location of extracapsular extension and positive surgical margins in radical prostatectomy specimens. J Urol 1992; 148: 331. Go to original source... Go to PubMed...
  20. Epstein JI. Evaluation of radical prostatectomy capsular margins of resection. The significance of margins designated as negative, closely approaching, and positive. Am J Surg Pathol 1990; 14: 626. Go to original source... Go to PubMed...
  21. Kim ED, Scardino PT, Hampel O, et al. Interposition of sural nerve restores function of cavernous nerves resected during radical prostatectomy. J Urol 1999; 161: 188. Go to original source... Go to PubMed...
  22. Secin FP, Koppie TM, Scardino PT, et al. Bilateral cavernous nerve interposition grafting during radical retropubic prostatectomy: Memorial Sloan-Kettering Cancer Center experience. J Urol 2007; 177: 664. Go to original source... Go to PubMed...
  23. Nelson BA, Chang SS, Cookson MS, Smith JA Jr. Morbidity and efficacy of genitofemoral nerve grafts with radical retropubic prostatectomy. Urology 2006; 67: 789. Go to original source... Go to PubMed...
  24. Briganti A, Chun FK, Salonia A, Gallina A, Farina E, Da Pozzo LF, Rigatti P, Montorsi F, Karakiewicz PI. Validation of a nomogram predicting the probability of lymph node invasion based on the extent of pelvic lymphadenectomy in patients with clinically localized prostate cancer. BJU Int 2006; 98(4): 788-793. Go to original source... Go to PubMed...
  25. Pound CR, Partin AW, Eisenberger MA, Chan DW, Pearson JD, Walsh PC. Natural history of progression after PSA elevation following radical prostatectomy. JAMA 1999; 281(17): 1591-1597. Go to original source... Go to PubMed...
  26. Aus G, Nordenskjöld K, Robinson D, Rosell J, Varenhorst E. Prognostic factors and survival in nodepositive (N1) prostate cancer - a prospective study based on data from a Swedish population-based cohort. Eur Urol 2003; 43(6): 627-631. Go to original source... Go to PubMed...
  27. Cheng L, Zincke H, Blute ML, Bergstrahl EJ, Scherer B, Bostwick DG. Risk of prostate carcinoma death in patients with lymph node metastasis. Cancer 2001; 91(1): 66-73. Go to original source...
  28. Bader P, Burkhard FC, Markwalder R, Studer UE. Is a limited lymph node dissection an adequate staging procedure for prostate cancer? J Urol 2002; 168(2): 514-518. Go to original source... Go to PubMed...
  29. Heidenreich A, et al. Guidelines on Prostate Cancer (pdf dokument). European Association of Urology 2009, dostupný z <http://www.uroweb.org/fileadmin/count.php?f=fileadmin%2Ftx_eauguidelines%2F2009%2FFull%2FProstate_Cancer.pdf>.
  30. Fallon B, Williams RD. Current options in the management of clinical stage C prostatic carcinoma. Urol Clin North Am 1990; 17(4): 853-866. Go to original source... Go to PubMed...
  31. Boccon-Gibod L, Bertaccini A, Bono AV, Dev Sarmah B, Höltl W, Mottet N, Tunn U, Zamboglou N. Management of locally advanced prostate cancer: a European Consensus. Int J Clin Pract 2003; 57(3): 187-194. Go to original source... Go to PubMed...
  32. Ward JF, Slezak JM, Blute ML, Bergstralh EJ, Zincke H. Radical prostatectomy for clinically advanced (cT3) prostate cancer since the advent of prostate-specific antigen testing: 15year outcome. BJU Int 2005; 95(6): 751-756. Go to original source... Go to PubMed...
  33. Hsu CY, Joniau S, Oyen R, Roskams T, Van Poppel H. Outcome of surgery for clinical unilateral T3a prostate cancer: a single-institution experience. Eur Urol 2007; 51(1): 121-128. Go to original source... Go to PubMed...
  34. Han M, Partin AW, Pound CR, Epstein JI, Walsh PC. Longterm biochemical disease-free and cancerspecific survival following anatomic radical retropubic prostatectomy. The 15-year Johns Hopkins experience. Urol Clin North Am 2001; 28(3): 555-565. Go to original source... Go to PubMed...
  35. Catalona WJ, Smith DJ. 5-year tumour recurrence rates after anatomical radical retropubic prostatectomy for prostate cancer. J Urol 1994; 152(5 Pt 2): 1837-1842. Go to original source... Go to PubMed...
  36. Hull GW, Rabbani F, Abbas F, Wheeler TM, Kattan MW, Scardino PT. Cancer control with radical prostatectomy alone in 1,000 consecutive patients. J Urol 2002; 167(2 Pt 1): 528-534. Go to original source... Go to PubMed...
  37. Trapasso JG, deKernion JB, Smith RB, Dorey F. The incidence and significance of detectable levels of serum prostate specific antigen after radical prostatectomy. J Urol 1994; 152(5 Pt 2): 1821-1825. Go to original source... Go to PubMed...
  38. Zincke H, Oesterling JE, Blute ML, Bergstralh EJ, Myers RP, Barrett DM. Long-term (15 years) results after radical prostatectomy for clinically localized (stage T2c or lower) prostate cancer. J Urol 1994; 152(5Pt2): 1850-1857. Go to original source... Go to PubMed...
  39. Grabe M, et al. Guidelines on Urological Infections. European Association of Urology 2009, dostupný z <http://www.uroweb.org/fileadmin/tx_eauguidelines/2009/Full/Urological_Infections.pdf>.
  40. Bolla M, van Poppel H, Collette L, et al. Preliminary results for EORTC trial 22911: radical prostatectomy followed by postoperative radiotherapy in prostate cancers with a high risk of progression. Cancer Radiother. 2007; 11(6-7): 363-369. Go to original source... Go to PubMed...
  41. Swanson GP, Hussey MA, Tangen CM, et al. Predominant treatment failure in postprostatectomy patients is local: Analysis of patterns of treatment failure in SWOG 8794. J Clin Oncol 2007; 25: 2225-2229. Go to original source... Go to PubMed...
  42. Wiegel T, Bottke D, Willich N, et al. Phase III results of adjuvant radiotherapy (RT) versus, ,wait and see" (WS) in patients with pT3 prostate cancer following radical prostatectomy (RP) (ARO 96-02/AUO AP 09/95). J Clin Oncol 2005; 23: 16(suppl; abstr 5060). Go to original source...




Oncology

Madam, Sir,
please be aware that the website on which you intend to enter, not the general public because it contains technical information about medicines, including advertisements relating to medicinal products. This information and communication professionals are solely under §2 of the Act n.40/1995 Coll. Is active persons authorized to prescribe or supply (hereinafter expert).
Take note that if you are not an expert, you run the risk of danger to their health or the health of other persons, if you the obtained information improperly understood or interpreted, and especially advertising which may be part of this site, or whether you used it for self-diagnosis or medical treatment, whether in relation to each other in person or in relation to others.

I declare:

  1. that I have met the above instruction
  2. I'm an expert within the meaning of the Act n.40/1995 Coll. the regulation of advertising, as amended, and I am aware of the risks that would be a person other than the expert input to these sites exhibited


No

Yes

If your statement is not true, please be aware
that brings the risk of danger to their health or the health of others.