Slovo úvodem

PhDr. Václav Mertin

Onkologie. 2013:7(6):271  

Neoadjuvant treatment of rectal adenocarcinoma

Igor Richter, Josef Dvořák, Jiří Bartoš

Onkologie. 2013:7(6):287-292  

Treatment of the rectal adenocarcinoma is multidisciplinary. Radiotherapy is the important component of the treatment. Neoadjuvant chemoradiotherapy is indicated in tumours T3–4 or in the case of positive lymph nodes. 5-fluorouracil (5-FU) and capecitabine are the most used cytostatik in combination with radiotherapy. The aim the neoadjuavnt treatment is attainment circumeferential radial margin (CRM) after total mesorectal excision (TME).

The tumor tissue bank as a source of new important information to predictive and prognostic factors in breast cancer

Alžběta Filipová, Zuzana Mačingová, Pavel Jandík, Pavel Měřička, Martina Řezáčová, Stanislav Filip

Onkologie. 2013:7(6):276-280  

The Tumor Tissue Bank containing cryopreserved samples unables development of new diagnostic methods based on molecular biologic and genetic analyses. Our study started in June 2008. In our study were taken and samples from 156 female patients. The results reported here represent the 3-year period of follow up. 316 women with breast carcinoma, mean age 65.2 years (age range 27 to 88 years) were admitted to this project. The aim of our study was to design a program of record-keeping and assessment of predictive and prognostic factors obtained with new molecular biologic and genetic methods. Utilization of new technologies in the treatment of...

Stereotactic radiotherapy and radiosurgery of primary brain tumors

Hana Doleželová, Petr Pospíšil, Pavel Šlampa, Irena Čoupková, Jan Garčič, Pavel Fadrus, Tomáš Svoboda, Iveta Selingerová, Ivana Horová

Onkologie. 2013:7(6):281-285  

We analysed retrospectively our treatment of primary brain tumors using stereotactic radiotherapy and radiosurgery. Methods: Patients underwent CT and MR examinations. Target volume and technique were planned in BrainLab system. Patients were irradiated on X knife. Radiosurgery was apllied with fixation using stereotactic frame. Stereotactic mask was used in cases of stereotactic radiotherapy. Statistical processing was performed at Department of mathematics and statistics, Faculty of Science, Masaryk university Brno. Results: 101 paients were included in our study. In the most of cases there were diagnosis of meningeoma and high-grade glioma....

Regorafenib v monoterapii u předléčeného metastatického kolorektálního karcinomu (CORRECT): mezinárodní multicentrická, randomizovaná, placebem kontrolovaná studie klinické fáze 3

Zdeněk Linke

Onkologie. 2013:7(6):298-300  

Mandibular angiosarcoma

Richard Pink, Patrik Flodr, Peter Tvrdý, Jindřich Pazdera

Onkologie. 2013:7(6):292-295  

Introduction: Malignant mesenchymal tumours of the orofacial region are extremely rare and comprise only 1% of all malignant orofacial tumours with more than 50 subtypes. Angiosarcomas are highly malignant neoplasms that originate from blood or lymphatic vessels. Angiosarcomas form 5,4 % of all sarcomas and in the head and neck region are the most frequent type of sarcoma. Aim: The aim of this case report is to describe a rare malignant neoplasm in the head and neck topography which can be diagnostic difficulty and may be missed or unrecognised with fatal consequences for the patient. Materials, methods, results: The authors describe the...

Multidisciplinary approach in the treatment of metastatic colorectal cancer

Lenka Ostřížková, Dagmar Brančíková, Zdeněk Mechl

Onkologie. 2013:7(6):296-297  

Colorectal cancer is the second most common cancer. At the time of diagnosis more than 30 % of patients have distant metastasis. The most common are liver metastases. Multidisciplinary approach to the treatment of liver metastases leads to longer survival of patients.

Cognitive-behavioral therapy in dying oncological patients

Jaroslava Raudenská, Alena Javůrková, Jiří Kozák

Onkologie. 2013:7(6):307-309  

Progresses of recent medicine markedly increased opportunities to treat oncological illnesses and support extension of patients´ lives. All the more space rises for psychoterapeutical interventions in terms of comprehensive treatment. People who face the end of the life due to oncological illness do so in many different settings. They may choose to remian at home, live with the family or others or move into extended care facilities, senior homes, or long term facilities. They may be of any age, from early teens to the indiem elderly. People, who find themselves suddenly living in hospital settings are faced with significant changes in their...

Needs Assessment Tools for Palliative Care

Radka Bužgová, Lucie Sikorová, Radka Kozáková, Darja Jarošová

Onkologie. 2013:7(6):310-314  

Palliative care emphasizes quality of life of the ill and the saturation of his bio-psycho-social and spiritual needs. Abroad are used tools for assessing needs of patients in oncological or palliative care, which helps to health workers to understand the specific needs of patients that could be subject to professional individualized care. The aim of this review is to analyse measuring tools for assessing needs of patients in palliative care, to compare them with recommended procedures for creation of measurement tools in palliative care and with Czech version of the questionnaire PNAP. In the electronic databases (Medline, Scopus, Proquest...

2013 International Multinational Association of Supportive Care in Cancer/International Society for Oral Oncology Symposium, June 27-29, 2013, Berlin, Germany

Ladislav Slováček

Onkologie. 2013:7(6):302-304  

Díky přesnější selekci pacientů s mCRC s vyloučením mutací více genů RAS může cetuximab ještě významněji prodloužit přežití: nové výsledky studie FIRE-3

Zuzana Zafarová

Onkologie. 2013:7(6):305