Onkologie. 2010:4(4):230-232
Nonmelanoma Skin Cancer
- Dermatovenerologická klinika LF UK a FN Plzeň
Nonmelanoma skin cancer (NMSC), encompassing basal cell carcinoma (BCC), squamous cell carcinoma (SCC), is the most frequent cancer
in fair-skinned populations, particularly frequent in coun tries with high sun exposure and in immu nosuppressed patients. The incidence
of NMSC has increased dramatically worldwide. Although BCC and SCC possess many similar features, there are fundamentals biological
differences. Actinic keratosis (AK) is thought to be part of a continuum along the path to the development of SCC. Most of the time the
diagnosis of NMSC is based on clinical presentation, however histological findings play in some cases main role. Whereas surgery remains
the gold-standard therapy for NMSC, noninvasive methods have shown promising results to treat superficial BCC, AK and subclinical lesions
on large body areas.
Keywords: skin cancer, basal cell carcinoma, squamous cell carcinoma, actinic keratosis, patched gene
Published: October 1, 2010 Show citation
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