Clinical stages in patients with multiple neoplasms

The results based in the Czech Cancer Registry in 1976–2005:

a) Of the 125,262 primary neoplasms (52.1 % males, 47.9 % females) there were registered 37.1 % of early clinical stages in males and

46.6 % in females, 9.3 % of advanced stages in males and 9.5 % in females. Unknown stages prevailed over the other stages until 1994.

The cancers of stage IV prevailed in males during the total period. The most of early stages were in Prague, of advanced stages in Pilsen

region. After exclusion of unknown stages, there were of 54,187 duplicities 63.8 % cases of early stages in males and 71.3 % in females;

18.4 % of advanced stages in males and 15.8 % in women. Of other 10,292 multiplicities there were 16.2 % of early stages in males and

11.7 % in females, 1.6 % of advanced stages in males and 1.2 % in females.

b) Of the 165,050 subsequent neoplasms (54.4 % males, 45.6 % females) – in cases following the primary stages I and II there were registered

21.7 % of early stages in males and 27 % in females, 5 % of advanced stages in males and 6 % in females, – in cases following the

primary stages III and IV there were registered 2.5 % of early stages in males and 3.2 % in females, 1.8 % of the advanced stages in males

and 2.2 % in females.

There were uncommon the number of 12,418 subsequent tumors of advanced stages in men (13.8 % of total 89,796 subsequent ones)

and 10,189 in women (13.5 % of total 75,254 subsequent ones), following the primary cancers of stages III, IV. Between these subsequent

and advanced stages predominated – in males 36.9 % cancers of gastrointestinal and 33.1 % respiratory tract, 10.3 % genital organs, 8.1 %

urinary tract, – in females 37 % cancers of gastrointestinum, 21 % breast, 17.2 % genital organs, 12.8 % respiratory and 4.5 % urinary tract.

It is worrying that of total multiple cases every the seventh gastrointestinal cancer in males and the fifth in females were detected at any

advanced clinical stages after primary cancer.

c) Of 41,161 survived up to October 2007 there were 54.7 % of early stages in males and 58 % in females, 5 % of advanced stages in males

and 5.2 % in females, unknown stages 40.3 % in males and 36.9 % in females. Of 84,101 deaths there were 30 % of early stages in males

and 39.8 % in females, 11 % of advanced stages in males and 12.1 % in females, unknown stages 59 % in males and 48.1 % in females.

The results can be suggested to list the multiple neoplasms and their clinical stages in the annual statistical reports of cancers in the

Czech population.

Keywords: multiple neoplasms, early and advanced clinical stages, their distribution