Onkologie. 2014:8(4):150-155

Follow-up of patients with pulmonary carcinoid 2002-2013

Ondřej Fischer¹, Juraj Kultan¹, Jana Kulísková¹, Ivona Grygárková¹, Vítězslav Kolek¹, Tomáš Tichý²

¹ Klinika plicních nemocí a tuberkulózy Lékařské fakulty Univerzity Palackého a Fakultní nemocnice Olomouc

² Ústav klinické a molekulární patologie Lékařské fakulty Univerzity, Olomouc

Carcinoid is a neuroendocrine tumour that can produce endocrine active substances. It represents 1-2 % of pulmonary tumours. Based

on histopathological characteristics, it is divided into typical and atypical carcinoid, which also affects the prognosis. {11,18} Typical

carcinoid (TC) has a favourable prognosis, is often found incidentally, and the five-year survival rate is over 90 %. Atypical carcinoid (AC)

exhibits a more aggressive behaviour, more frequent metastasizing, and a lower five-year survival rate (40-60 %). {5,11} We followed up

a group of 52 patients with a histologically confirmed diagnosis of carcinoid who were treated at our clinic in the years 2002 to 2013.

Typical carcinoid was diagnosed in 35 patients (67 %) and 17 patients (33 %) had atypical carcinoid. The follow-up confirmed the incidence

rates and prognosis of patients reported in the literature, while analyzing the options and efficacy of endobronchial treatment and the

results of treatments for both types of tumours. Interestingly, a high incidence of double (as well as triple) malignancies was found in

patients with atypical carcinoid (25 % of patients).

Keywords: carcinoid, typical carcinoid, atypical carcinoid, neuroendocrine tumors of the lung, follow-up

Published: October 1, 2014  Show citation