Onkologie. 2019:13(1):14-18 | DOI: 10.36290/xon.2019.003

Breast cancer and pregnancy

Zuzana Bielčiková

Onkologická klinika VFN a 1. LF UK v Praze

Breast cancer (BC) and pregnancy can be viewed from several perspectives (see points below). Current knowledge and recommendations by their complexity include all of them and can be summarized as follows: 1. Pregnancy planning in women after treatment for BC: „„there is no doubt about the safety of pregnancy in women after treatment of BC, „„the optimum gap between treatment of BC and pregnancy is the subject of ongoing studies. 2. Fertility preservation in BC patients: „„optimal strategy includes oocyte/embryo cryopreservation in the period prior to chemotherapy and LHRH analogue administration during its course. 3. Management of gestational BC treatment: „„gestational BC therapy should mimic as much as possible the treatment of non-pregnant women, „„chemotherapy can be applied in the 2nd and 3rd trimester of pregnancy, breast surgery and sentinel node scintigraphy is generally possible at any time during pregnancy, endocrine therapy, targeted anti-HER2 therapy must be postponed for the postpartum period, „„induction of abortion has no effect on the prognosis of mother.

Keywords: breast cancer, pregnancy, fertility preservation, gestational breast cancer, breast cancer in young women, chemotherapy-induced infertility

Published: March 15, 2019  Show citation