Onkologie 2020: 14(Suppl.B): 30-33 | DOI: 10.36290/xon.2020.032

Isolated axial lymphadenopathy as the first symptom of squamous cell carcinoma of the vulva

Jana Mergancová^1,2,7, Jindřiška Mergancová¹, Kamila Černotová¹, Edita Šnáblová², Mária Hácová^3,6, Aleš Hlávka^4,5, Prokop Homola⁸

¹ Chirurgická klinika, Pardubická nemocnice, Nemocnice Pardubického kraje, a. s.

² EUC klinika, a. s., Pardubice

³ Oddělení patologie, Pardubická nemocnice, Nemocnice Pardubického kraje, a. s.

⁴ Komplexní onkologické centrum Pardubického kraje, Multiscan, s. r. o., Pardubice

⁵ Oddělení klinické a radiační onkologie, Pardubická nemocnice, Nemocnice Pardubického kraje, a. s.

⁶ Fakulta zdravotnických studií Pardubice, Univerzita Pardubice

⁷ Lékařská fakulta, Univerzita Palackého v Olomouci

⁸ Porodnicko-gynekologická klinika, Pardubická nemocnice, Nemocnice Pardubického kraje, a. s.

The most common causes of malignant axillary lymphadenopathy include secondary impairment of the breast cancer, malignant melanoma and haemato-oncological disease. Descriptions of axial metastases with primary tumours of the lungs, gastrointestinal tract, ovaria and/or testicle or hypopharynx are rarely found in medical literature. To determine a differential diagnosis, we focus mainly on results from histological examinations and from other examinations such as mammological, dermatological, endoscopic, pulmonary or ENT. Multi-disciplinary commissions usually come out with such diagnoses very often. We present in our paper the case history of an 86-year-old female with numerous thoracic skin manifestations to the spinal cellular carcinomas in situ and with a distinctive lymphadenopathy in her axilla, where the described pathogen was a squamous cell carcinoma. All the above-mentioned examinations have not led to any revealing of the primary tumour. After four months the patient came complaining of vaginal bleeding. The oncological surgeon discovered a vulvar tumour, which was subsequently confirmed also by the gynaecologist. Furthermore, the pathologists concluded with the squamous cell carcinoma diagnosis as being a primary origin axillary lymphadenopathy which was an unusual only symptom of the disease. The solitary vaginal or vulvar metastases in axillary nodes have of yet to be recorded in any medical article.

Keywords: axial lymphadenopathy, vulvar carcinoma, Bowen´s dermatosis.

Published: June 2, 2020  Show citation