Onkologie. 2014:8(3):121-123
Allogeneic stem cell transplantation in treating haematological malignancies in children
- Klinika dětské hematologie a onkologie
- Fakultní nemocnice v Motole a 2. lékařská fakulta Univerzity Karlovy v Praze
Allogeneic haematopoietic stem cell transplantation is a therapeutic method in a wide range of malignant or non-malignant diseases.
Healthy cells of a suitable donor replace missing, malignant, or non-functional recipient's cells. The donor's immune system ensures
protection from infections while reducing the risk of disease recurrence. However, it can cause damage to the recipient's healthy tissue
(graft-versus-host disease). The sources of stem cells can include the bone marrow, stimulated peripheral blood stem cells, or umbilical-
-cord blood from a suitable related or anonymous donor from a registry.
Keywords: allogeneic transplantation, malignant disease of blood, children, search for donor, late effects of the disease
Published: June 1, 2014 Show citation
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