Adventní rozjímání

prof. MUDr. Vladimír Mihál, CSc.

Onkologie. 2010:4(6):327  

Karcinom pankreatu - slovo úvodem

Roman Havlík

Onkologie. 2010:4(6):332  

Pancreatic cancer - surgical treatment strategy

Miroslav Ryska

Onkologie. 2010:4(6):333-337  

Radical resection is only method of treatment giving the chance for long-term survival in the patients with pancreatic cancer with 5-year survival 11–28 %. Czech Republic is in the incidence of pancreatic cancer in the 6.place in Europe. 70–80 % patients are irresectable in the moment of diagnosis. Patients with staging of T1-3, N0-1, M0 are indicated for radical resection with standard lymphadenectomy, resection of portomesenteric segment is indicated as a part of R0 resection. In the case of advanced carcinoma over that staging in patients in good condition palliative resection or biliodigestive anastomosis is indicated, in...

Surgery for cancer of head of pancreas and survival analysis

Martin Loveček, Dušan Klos, Pavel Skalický, Jiří Kysučan, Čestmír Neoral, Bohuslav Melichar, Roman Havlík

Onkologie. 2010:4(6):338-341  

The authors refer seventy six patients radically operated for pancreatic head carcinoma and analyzed postoperative complications and survival. Material and Methods: During 1/2006–9/2010 76 patients underwent potentially curative hemipancreato-duodenectomy for adenocarcinoma of the head of pancreas. The patients are prospectively followed, complications and survival are discussed. Results: The 30-days postoperative mortality was 2,6 %. According to TNM classification 11 % of patients had stage I, 78 % stage II and 3 % stage III. Most severe complications were leak from pancreato-jejunal anastomosis (6,5 %) and delayed gastric emptying...

Synchronous invasive ductal pancreatic adenocarcinomas and its clinical importance

Roman Havlík, Martin Loveček, Dušan Klos, Mohamed Ghothim, Čestmír Neoral

Onkologie. 2010:4(6):342-343  

The authors refer two cases of incidentally founded synchronous pancreatic tumors in the remaining pancreas following partial pancreatic resection for adenocarcinoma of the head of the pancreas. The reasons for removing the retained pancreas were postoperative complications. The frequency of these synchronous tumors is discussed with regards to the newly described development of pancreatic adenocarcinoma from pancreatic ductal intraepithelial neoplasia. The possible clinical importance of these silent synchronous tumors in clinical praxis is discussed.

Pancreatic neuroendocrine tumors therapy - surgeon’s perspective

Zdeněk Kala, Jan Hlavsa, Vladimír Procházka, Petr Kysela, Filip Marek, Roman Svatoň

Onkologie. 2010:4(6):344-348  

The authors put forward a review article summarizing current opinion in diagnostics and therapy of pancreatic neuroendocrine tumors. They present actual TNM classification of these tumors highlighting CT, MRI, EUS and octreoscan as standard imaging methods. In the field of therapy, radical, R0 resection, which brings the best overall survival, is accented. They also accept the possibility of debulking resections and liver transplantation in the cases of local advanced and metastatic disease respectively. They point out the different prognosis of pancreatic neuroendocrine tumors and pancreatic cancer. At the end the authors emphasize the importace...

The contribution of computed tomography and magnetic resonance imaging to the staging of tumour disease

Andrea Burgetová, Daniela Fischerová, Manuela Vaněčková, Zdeněk Seidl

Onkologie. 2010:4(6):349-352  

in oncogynaecology The using modern imaging methods in preoperative staging, therapeutic management and dispenzarization of oncological patients contribute to high success of treatment of gynaecological malignant tumours. The cumulative complexity but also complicity of diagnostics is a challenge for radiologist, gynaecologist and oncologist to learn to use these techniques in effective way from both clinical and economical points of view. This project is the review of possibilities of imaging modalities focused on CT (computed tomography) and MRI (magnetic resonance imaging). We present their advantages and disadvantages with the emphasis...

Current perspective on surgical treatment of DCIS

Jiří Gatěk

Onkologie. 2010:4(6):353-356  

Breast screening results in an ever-increasing proportion of ductal carcinoma in situ (DCIS) in the spectrum of newly detected breast cancers. It is a heterogeneous group of tumours. DCIS without microinvasion does not extend beyond the basal membrane and metastasize. Although it accounts for up to 20 % of breast cancers in countries with advanced screening programmes, there is a lot of controversy over its classification and treatment. Breast conservative procedures that are an alternative to mastectomy in early breast cancer have been included in the treatment of DCIS as well. There is still no consensus on the width of the resection margin....

Clinical stages in patients with multiple neoplasms

Edvard Geryk, Petr Dítě, Jan Trna, Jiří Kozel, Milan Konečný

Onkologie. 2010:4(6):357-361  

The results based in the Czech Cancer Registry in 1976–2005: a) Of the 125,262 primary neoplasms (52.1 % males, 47.9 % females) there were registered 37.1 % of early clinical stages in males and 46.6 % in females, 9.3 % of advanced stages in males and 9.5 % in females. Unknown stages prevailed over the other stages until 1994. The cancers of stage IV prevailed in males during the total period. The most of early stages were in Prague, of advanced stages in Pilsen region. After exclusion of unknown stages, there were of 54,187 duplicities 63.8 % cases of early stages in males and 71.3 % in females; 18.4 % of advanced stages in males and...

Desmoplastic small round cell tumor

Viktor Maňásek, Renata Soumarová

Onkologie. 2010:4(6):362-367  

Desmoplastic small round cell tumor (DSRCT) is a rare disease from sarcoma group family. Typically, there is an extensive infiltration of abdominal cavity, peritoneal effusion with no evident primary origin of tumor. Prognosis is unfavourable with 5-years overall survival described in 15 % of cases even though multimodal treatment strategy is performed. We introduce case report of 34-years old patient with DSRCT treated in our Oncology center. Reasonable schema of differential diagnosis of soft-tissue expansion in abdominal cavity is mentioned and we emphasize crucial role of molecular genetic analysis. We focus on therapeutic approaches of...

ESMO Congress 2010: head and neck cancers

Zdeněk Mechl, Jana Neuwirthová

Onkologie. 2010:4(6):368-370  

HPV – associated head and neck cancer represent a new chapter in the therapy of head and neck cancer. Considerations for integrating targeted therapies into the current treratments for head and neck treatmens are more or less stabilized. No new effective drugs were introduced. There is again discussion about the usefullnes of induction chemotherapy in the therapy of locally advanced tumors or preservation protocols.

Autodidaktický test 6/2010

Onkologie. 2010:4(6):371